urod.S uroporphyrinogen decarboxylase S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: urod.S
Official Full Name: uroporphyrinogen decarboxylase S homeolog
Primary source: Xenbase:XB-GENE-948499
Locus tag: XELAEV_18025194mg
See related: EnsemblRapid:ENSXLAG00005012998
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: urod
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Genomic context

Location:: chromosome: 4S

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (70754536..70769335)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (64526300..64538467)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables carboxy-lyase activity	IEA Inferred from Electronic Annotation more info
enables uroporphyrinogen decarboxylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within heme biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within porphyrin-containing compound biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within porphyrin-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protoporphyrinogen IX biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uroporphyrinogen decarboxylase

NP_001084556.1

EC 4.1.1.37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091087.1 → NP_001084556.1 uroporphyrinogen decarboxylase

See identical proteins and their annotated locations for NP_001084556.1

Status: PROVISIONAL

Source sequence(s)

BC068896

UniProtKB/TrEMBL

A0A974CZ94, Q6NTR0

Related

ENSXLAP00005038308.1, ENSXLAT00005039220.1

Conserved Domains (1) summary

cd00717
Location:21 → 360

URO-D; Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction ...