rc3h1.L ring finger and CCCH-type domains 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rc3h1.L
Official Full Name: ring finger and CCCH-type domains 1 L homeolog
Primary source: Xenbase:XB-GENE-5864202
Locus tag: XELAEV_18023230mg
See related: EnsemblRapid:ENSXLAG00005031708 AllianceGenome:Xenbase:XB-GENE-5864202
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rc3h1
Summary: Predicted to enable RNA binding activity and ubiquitin-protein transferase activity. Predicted to act upstream of or within cellular response to interleukin-1; protein polyubiquitination; and regulation of mRNA stability. Predicted to be located in P-body and cytoplasmic stress granule. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 4L

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (93355365..93400099)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (88065179..88109921)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA stem-loop binding	IEA Inferred from Electronic Annotation more info
enables RNA stem-loop binding	ISS Inferred from Sequence or Structural Similarity more info
enables double-stranded RNA binding	IEA Inferred from Electronic Annotation more info
enables double-stranded RNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA 3'-UTR binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within 3'-UTR-mediated mRNA destabilization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within cellular response to interleukin-1	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of mRNA catabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within post-transcriptional regulation of gene expression	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein polyubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein polyubiquitination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in P-body	IEA Inferred from Electronic Annotation more info
located_in P-body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic stress granule	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic stress granule	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: roquin-1

Names: RING finger and C3H zinc finger protein 1; RING finger and CCCH-type zinc finger domain-containing protein 1; probable E3 ubiquitin-protein ligase Roquin; ring finger and CCCH-type zinc finger domains 1; roquin

NP_001084548.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.