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acap2.S rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 414474, updated on 17-Aug-2024

Summary

Official Symbol
acap2.S
Official Full Name
rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog
Primary source
Xenbase:XB-GENE-6252841
Locus tag
XELAEV_18029659mg
See related
EnsemblRapid:ENSXLAG00005008232
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
acap2; acap3; centb2; centb5; cnt-b2; acap3.L
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Genomic context

See acap2.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
24
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (92760198..92819807)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (87300770..87330145)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxybutyrate dehydrogenase, type 1 A pseudogene S homeolog Neighboring gene 3-hydroxybutyrate dehydrogenase, type 1 B S homeolog Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 S homeolog Neighboring gene uncharacterized LOC121394270 Neighboring gene xyloside xylosyltransferase 1 S homeolog Neighboring gene family with sequence similarity 43 member A S homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC81056

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog
Names
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091058.1NP_001084527.1  rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog

    See identical proteins and their annotated locations for NP_001084527.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068667
    UniProtKB/TrEMBL
    Q6NUC8
    Related
    ENSXLAP00005023707.1, ENSXLAT00005024413.1
    Conserved Domains (2) summary
    cl12013
    Location:18217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl17171
    Location:269287
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    92760198..92819807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041563972.1XP_041419906.1  rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1KRH6
    Related
    ENSXLAP00005023803.1, ENSXLAT00005024511.1
    Conserved Domains (6) summary
    PTZ00322
    Location:636707
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    cd07638
    Location:18217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    COG0666
    Location:541708
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:269372
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:591617
    ANK; ANK repeat [structural motif]
    cd08851
    Location:404519
    ArfGap_ACAP2; ArfGAP domain of ACAP2 (ArfGAP with Coiled-coil, ANK repeat and PH domains 2)
  2. XM_041563970.1XP_041419904.1  rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KUK4
    Related
    ENSXLAP00005023816.1, ENSXLAT00005024524.1
    Conserved Domains (5) summary
    PTZ00322
    Location:667738
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    cd07638
    Location:18217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    cd13250
    Location:269372
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:622648
    ANK; ANK repeat [structural motif]
    cd08851
    Location:404519
    ArfGap_ACAP2; ArfGAP domain of ACAP2 (ArfGAP with Coiled-coil, ANK repeat and PH domains 2)
  3. XM_041563971.1XP_041419905.1  rfGAP with coiled-coil, ankyrin repeat and PH domains 2 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A1L8G3U3, A0A974CRT1
    Related
    ENSXLAP00005023834.1, ENSXLAT00005024542.1
    Conserved Domains (5) summary
    cd07638
    Location:18217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    cd13250
    Location:269365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:615641
    ANK; ANK repeat [structural motif]
    cd08851
    Location:397512
    ArfGap_ACAP2; ArfGAP domain of ACAP2 (ArfGAP with Coiled-coil, ANK repeat and PH domains 2)
    pfam12796
    Location:615709
    Ank_2; Ankyrin repeats (3 copies)