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ube4a.S ubiquitination factor E4A S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 414451, updated on 4-Nov-2024

Summary

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Official Symbol
ube4a.S
Official Full Name
ubiquitination factor E4A S homeolog
Primary source
Xenbase:XB-GENE-922265
Locus tag
XELAEV_18037410mg
See related
EnsemblRapid:ENSXLAG00005025152 AllianceGenome:Xenbase:XB-GENE-922265
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ube4a
Summary
Predicted to enable ubiquitin-ubiquitin ligase activity. Predicted to act upstream of or within ERAD pathway; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ubiquitin ligase complex. Orthologous to human UBE4A (ubiquitination factor E4A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ube4a.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (70807724..70826622, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (52327907..52346936)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121396158 Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene CD3g molecule S homeolog Neighboring gene CD3e molecule S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114906

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ubiquitin-ubiquitin ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ERAD pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquitination factor E4A S homeolog
Names
ubiquitination factor E4A (UFD2 homolog)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091037.1 → NP_001084506.1  ubiquitination factor E4A S homeolog

    See identical proteins and their annotated locations for NP_001084506.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098986
    UniProtKB/TrEMBL
    A0A974HA54, Q4FZX1
    Related
    ENSXLAP00005074746.1, ENSXLAT00005076326.1
    Conserved Domains (3) summary
    COG5113
    Location:177 → 1065
    UFD2; Ubiquitin fusion degradation protein 2 [Posttranslational modification, protein turnover, chaperones]
    pfam04564
    Location:990 → 1062
    U-box; U-box domain
    pfam10408
    Location:329 → 973
    Ufd2P_core; Ubiquitin elongating factor core

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    70807724..70826622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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