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ADCYAP1 adenylate cyclase activating polypeptide 1 [ Sus scrofa (pig) ]

Gene ID: 414283, updated on 17-Aug-2024

Summary

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Official Symbol
ADCYAP1provided by VGNC
Official Full Name
adenylate cyclase activating polypeptide 1provided by VGNC
Primary source
VGNC:VGNC:85114
See related
Ensembl:ENSSSCG00000035186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
PACAP
Expression
Low expression observed in reference dataset See more
Orthologs
human mouse all
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Genomic context

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See ADCYAP1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (105414628..105422294, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (98531534..98539159, complement)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene classical arabinogalactan protein 9-like Neighboring gene uncharacterized LOC102163958 Neighboring gene uncharacterized LOC102165393 Neighboring gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-like Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Single nucleotide polymorphism identification, linkage and radiation hybrid mapping of the porcine pituitary adenylate cyclase-activating polypeptide type I receptor gene to chromosome 18. Kollers S, et al. J Anim Breed Genet, 2006 Dec. PMID 17177700
  2. Co-expression of PACAP with VIP, SP and CGRP in the porcine nodose ganglion sensory neurons. Rytel L, et al. Anat Histol Embryol, 2015 Apr. PMID 24713103
  3. VIP induces the translocation and degradation of the alpha subunit of Gs protein in rat pituitary GH4C1 cells. Yajima Y, et al. J Biochem, 1998 Jun. PMID 9603988
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables neuropeptide hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pituitary adenylate cyclase activating polypeptide activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perikaryon IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pituitary adenylate cyclase-activating polypeptide
Names
adenylate cyclase activating peptide, pituitary 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001544.1 → NP_001001544.1  pituitary adenylate cyclase-activating polypeptide precursor

    See identical proteins and their annotated locations for NP_001001544.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ715856
    UniProtKB/Swiss-Prot
    O97570, P41535, Q6KBX3
    UniProtKB/TrEMBL
    A0A8D0X7C2, A0A8D1XWR6
    Conserved Domains (1) summary
    pfam00123
    Location:132 → 158
    Hormone_2; Peptide hormone

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    105414628..105422294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005665307.3 → XP_005665364.1  pituitary adenylate cyclase-activating polypeptide isoform X1

    UniProtKB/TrEMBL
    A0A287BEZ0, A0A4X1VPG7, A0A8D0S527, A0A8D0X7C2, A0A8D1XWR6
    Related
    ENSSSCP00000054892.1, ENSSSCT00000055920.3
    Conserved Domains (1) summary
    pfam00123
    Location:132 → 158
    Hormone_2; Peptide hormone

  2. XM_021093591.1 → XP_020949250.1  pituitary adenylate cyclase-activating polypeptide isoform X1

    UniProtKB/TrEMBL
    A0A287BEZ0, A0A4X1VPG7, A0A8D0S527, A0A8D0X7C2, A0A8D1XWR6
    Conserved Domains (1) summary
    pfam00123
    Location:132 → 158
    Hormone_2; Peptide hormone
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41535.3 GenPept UniProtKB/Swiss-Prot:P41535

Gene LinkOut

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