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lepA translation elongation factor 4 [ [Eubacterium] eligens ATCC 27750 ]

Gene ID: 41355481, updated on 29-Feb-2024

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
EUBELI_RS03535
Gene type
protein coding
Organism
[Eubacterium] eligens ATCC 27750 (strain: ATCC 27750, culture-collection: ATCC:27750, type-material: type strain of Eubacterium eligens)
Lineage
Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnospira
Old locus tag
EUBELI_00737
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Genomic context

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Sequence:
NC_012778.1 (742048..743862)

NC_012778.1Genomic Context describing neighboring genes Neighboring gene N-acetylmuramoyl-L-alanine amidase Neighboring gene RNA polymerase sporulation sigma factor SigE Neighboring gene radical SAM family heme chaperone HemW Neighboring gene helix-turn-helix domain-containing protein Neighboring gene ammonium transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_012778.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  2. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  3. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
  4. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article
  5. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Mahowald MA, et al. Proc Natl Acad Sci U S A, 2009 Apr 7. PMID 19321416, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
translation elongation factor 4
WP_012738981.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012778.1 Reference assembly

    Range
    742048..743862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_012738981.1 translation elongation factor 4 [Lachnospira eligens]

    See identical proteins and their annotated locations for WP_012738981.1

    UniProtKB/Swiss-Prot
    C4Z541
    Conserved Domains (1) summary
    PRK05433
    Location:5 → 604
    PRK05433; GTP-binding protein LepA; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C4Z541.1