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CG31388 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41355, updated on 2-Nov-2024

Summary

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Official Symbol
CG31388provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051388
Locus tag
Dmel_CG31388
See related
AllianceGenome:FB:FBgn0051388
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH10523; CG17722; CG5135; Dmel\CG31388
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in organism. Orthologous to human ZNF707 (zinc finger protein 707) and ZNF746 (zinc finger protein 746). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG31388 in Genome Data Viewer
Location:
86D8-86D8; 3-50 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11237815..11240114)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7063537..7065836)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene SCP-containing protein B Neighboring gene SCP-containing protein A Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid. Li M, et al. PLoS One, 2023. PMID 36595500, Free PMC Article
  2. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
  3. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
  4. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
  5. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Nitta KR, et al. Elife, 2015 Mar 17. PMID 25779349, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription cis-regulatory region binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31388-PA
CG31388-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11237815..11240114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260113.1 → NP_001247042.1  uncharacterized protein Dmel_CG31388, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247042.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K731
    Conserved Domains (1) summary
    pfam07776
    Location:4 → 76
    zf-AD; Zinc-finger associated domain (zf-AD)

  2. NM_141803.3 → NP_650060.1  uncharacterized protein Dmel_CG31388, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650060.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2T4, Q95SP3, Q9VGQ5
    Related
    FBpp0081832
    Conserved Domains (2) summary
    sd00017
    Location:286 → 306
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07776
    Location:4 → 76
    zf-AD; Zinc-finger associated domain (zf-AD)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K731 A0A0B4K731
Q9VGQ5 Q9VGQ5

Gene LinkOut

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