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alphaTub85E alpha-Tubulin at 85E [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41183, updated on 2-Nov-2024

Summary

Official Symbol
alphaTub85Eprovided by FlyBase
Official Full Name
alpha-Tubulin at 85Eprovided by FlyBase
Primary source
FLYBASE:FBgn0003886
Locus tag
Dmel_CG9476
See related
AllianceGenome:FB:FBgn0003886
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
2t; 85E; a2t; ALPHA 85E; alpha-tub; alpha-Tub; alpha-Tub85E; alpha-tubulin; alpha2; alpha2t; alpha85E; alpha85E-tub; alphaTub; alphaTub2; alphaTub84E; alphatub85E; aTub85E; CG9476; Dmel\CG9476; DTA3; T; Tub; Tub1D; TUBA85E
Summary
A structural constituent of cytoskeleton. Involved in unidimensional cell growth. Located in cytoplasmic microtubule and spindle microtubule. Is expressed in several structures, including adult head; embryonic hindgut; imaginal disc; larval muscle cell; and sensory organ cell. Orthologous to human TUBA1B (tubulin alpha 1b) and TUBA1C (tubulin alpha 1c). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See alphaTub85E in Genome Data Viewer
Location:
85E6-85E6; 3-49 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9731221..9733250, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5556943..5558972, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene dalmatian Neighboring gene hyperplastic discs Neighboring gene Forkhead box P Neighboring gene sidestep VII Neighboring gene Pinin

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in unidimensional cell growth IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasmic microtubule IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microtubule IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in spindle microtubule IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
alpha-Tubulin at 85E
Names
CG9476-PA
alpha tubulin
alpha-Tubulin
alpha-Tubulin 85E
alpha2-tubulin
alpha2tubulin
alpha85E-tubulin
alphaT
alphaTub85E-PA
alphatubulin
tubulin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9731221..9733250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079573.5NP_524297.1  alpha-Tubulin at 85E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524297.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B5RJ60, P06604, Q8MYS4, Q9VH86
    UniProtKB/TrEMBL
    K7WKV5, K7XI11
    Related
    FBpp0081565
    Conserved Domains (1) summary
    PTZ00335
    Location:1448
    PTZ00335; tubulin alpha chain; Provisional