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CG8301 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41160, updated on 2-Nov-2024

Summary

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Official Symbol
CG8301provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037717
Locus tag
Dmel_CG8301
See related
AllianceGenome:FB:FBgn0037717
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8301
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human ZNF311 (zinc finger protein 311) and ZNF578 (zinc finger protein 578). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG8301 in Genome Data Viewer
Location:
85D26-85D27; 3-48 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9581306..9586648)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5407028..5412370)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene karyopherin alpha3 Neighboring gene Son RNA binding protein Neighboring gene uncharacterized protein Neighboring gene P58IPK Neighboring gene bocksbeutel Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hrp59, an hnRNP M protein in Chironomus and Drosophila, binds to exonic splicing enhancers and is required for expression of a subset of mRNAs. Kiesler E, et al. J Cell Biol, 2005 Mar 28. PMID 15781475, Free PMC Article
  2. Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. Pek JW, et al. J Cell Biol, 2015 Oct 26. PMID 26504165, Free PMC Article
  3. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
  4. Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Kankel MW, et al. Genetics, 2020 Jul. PMID 32345615, Free PMC Article
  5. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8301-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9581306..9586648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141658.5 → NP_649915.1  uncharacterized protein Dmel_CG8301 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649915.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHA9
    Related
    FBpp0081551
    Conserved Domains (3) summary
    COG5048
    Location:198 → 508
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:480 → 500
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07776
    Location:3 → 87
    zf-AD; Zinc-finger associated domain (zf-AD)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHA9 Q9VHA9

Gene LinkOut

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