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CG1307 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40814, updated on 2-Nov-2024

Summary

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Official Symbol
CG1307provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0026566
Locus tag
Dmel_CG1307
See related
AllianceGenome:FB:FBgn0026566
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS00004.12; Dmel\CG1307
Summary
Predicted to enable aminoacyl-tRNA hydrolase activity. Predicted to be active in cytosol and mitochondrion. Is expressed in adult head; adult heart; and organism. Orthologous to human PTRH2 (peptidyl-tRNA hydrolase 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG1307 in Genome Data Viewer
Location:
84A1-84A1; 3-48 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6656030..6657442, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2481752..2483504, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene sungrazer Neighboring gene uncharacterized protein Neighboring gene Argininosuccinate synthase Neighboring gene TBP-associated factor 1 Neighboring gene twisted bristles roughened eye Neighboring gene O-6-alkylguanine-DNA alkyltransferase Neighboring gene labial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fine-scale genetic mapping of a hybrid sterility factor between Drosophila simulans and D. mauritiana: the varied and elusive functions of "speciation genes". Araripe LO, et al. BMC Evol Biol, 2010 Dec 14. PMID 21144061, Free PMC Article
  2. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article
  3. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article
  4. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100
  5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aminoacyl-tRNA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aminoacyl-tRNA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1307-PC
CG1307-PE
hypothetical 23.1kd-like protein
NP_001287202.1
NP_649675.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6656030..6657442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300273.1 → NP_001287202.1  uncharacterized protein Dmel_CG1307, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287202.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O97067, Q8MR09, Q9VI42
    UniProtKB/TrEMBL
    E1JJ73
    Conserved Domains (1) summary
    cd02430
    Location:72 → 186
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

  2. NM_141418.4 → NP_649675.2  uncharacterized protein Dmel_CG1307, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649675.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O97067, Q8MR09, Q9VI42
    UniProtKB/TrEMBL
    E1JJ73
    Conserved Domains (1) summary
    cd02430
    Location:72 → 186
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JJ73 E1JJ73
O97067.2 O97067

Gene LinkOut

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