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srsf6 serine/arginine-rich splicing factor 6 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 407954, updated on 4-Nov-2024

Summary

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Official Symbol
srsf6provided by Xenbase
Official Full Name
serine/arginine-rich splicing factor 6provided by Xenbase
Primary source
Xenbase:XB-GENE-488901
See related
Ensembl:ENSXETG00000045970 AllianceGenome:Xenbase:XB-GENE-488901
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
b52; sfrs4; sfrs6; srp55
Summary
Predicted to enable RNA binding activity. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to human SRSF6 (serine and arginine rich splicing factor 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See srsf6 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
7
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (39851509..39860831)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (31463310..31472582)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene erythrocyte membrane protein band 4.1-like 1 Neighboring gene uncharacterized LOC116408016 Neighboring gene L3MBTL1, histone methyl-lysine binding protein Neighboring gene MATH and LRR domain-containing protein PFE0570w-like Neighboring gene serum/glucocorticoid regulated kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC69488, MGC76055

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arginine/serine-rich splicing factor 4
Names
splicing factor, arginine/serine-rich 4
splicing factor, arginine/serine-rich 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001248.1 → NP_001001248.1  arginine/serine-rich splicing factor 4 isoform 1

    See identical proteins and their annotated locations for NP_001001248.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068213
    UniProtKB/TrEMBL
    Q6NVB3
    Related
    ENSXETP00000107903.1, ENSXETT00000107817.1
    Conserved Domains (4) summary
    cd12596
    Location:3 → 72
    RRM1_SRSF6; RNA recognition motif 1 in vertebrate serine/arginine-rich splicing factor 6 (SRSF6)
    cd12600
    Location:106 → 176
    RRM2_SRSF4_like; RNA recognition motif 2 in serine/arginine-rich splicing factor 4 (SRSF4) and similar proteins
    cl25887
    Location:325 → 453
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl28310
    Location:220 → 403
    Rho; Transcription termination factor Rho [Transcription]

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    39851509..39860831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031894022.1 → XP_031749882.1  arginine/serine-rich splicing factor 4 isoform X1

    UniProtKB/TrEMBL
    A0A803JW78
    Related
    ENSXETP00000112302.1, ENSXETT00000112084.1
    Conserved Domains (4) summary
    PRK12678
    Location:220 → 370
    PRK12678; transcription termination factor Rho; Provisional
    TIGR01642
    Location:314 → 442
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cd12596
    Location:1 → 72
    RRM1_SRSF6; RNA recognition motif 1 (RRM1) found in vertebrate serine/arginine-rich splicing factor 6 (SRSF6)
    cd12766
    Location:106 → 178
    RRM2_SRSF6; RNA recognition motif 2 (RRM2) found found in vertebrate serine/arginine-rich splicing factor 6 (SRSF6)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001016477.2: Suppressed sequence

    Description
    NM_001016477.2: This RefSeq was temporarily suppressed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version

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