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tars1 threonyl-tRNA synthetase 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 407892, updated on 4-Nov-2024

Summary

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Official Symbol
tars1provided by Xenbase
Official Full Name
threonyl-tRNA synthetase 1provided by Xenbase
Primary source
Xenbase:XB-GENE-975289
See related
Ensembl:ENSXETG00000009868 AllianceGenome:Xenbase:XB-GENE-975289
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
tars; tarsl2
Summary
Predicted to enable ATP binding activity and threonine-tRNA ligase activity. Predicted to act upstream of or within threonyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 7. Orthologous to human TARS1 (threonyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See tars1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (200079216..200113637, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (186811619..186845276, complement)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene relaxin family peptide receptor 3 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 12 Neighboring gene uncharacterized LOC116408352 Neighboring gene chromosomal serine/threonine-protein kinase JIL-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC69451

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity, acting on a tRNA IEA
Inferred from Electronic Annotation
more info
  
enables threonine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within threonyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
threonine--tRNA ligase 1, cytoplasmic
Names
threonyl-tRNA synthetase-like 2
NP_001001219.1
XP_012809310.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001219.2 → NP_001001219.1  threonine--tRNA ligase 1, cytoplasmic

    See identical proteins and their annotated locations for NP_001001219.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067949
    UniProtKB/TrEMBL
    A0A6I8SL97, F6SGS0, Q6NVQ6
    Related
    ENSXETP00000021733.4, ENSXETT00000021733.5
    Conserved Domains (1) summary
    PLN02908
    Location:49 → 714
    PLN02908; threonyl-tRNA synthetase

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    200079216..200113637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012953856.3 → XP_012809310.1  threonine--tRNA ligase 1, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A6I8SL97, A0A8J0S602
    Conserved Domains (1) summary
    PLN02908
    Location:48 → 713
    PLN02908; threonyl-tRNA synthetase
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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