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TRPC5 transient receptor potential cation channel subfamily C member 5 [ Bos taurus (domestic cattle) ]

Gene ID: 407103, updated on 4-Oct-2024

Summary

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Official Symbol
TRPC5provided by VGNC
Official Full Name
transient receptor potential cation channel subfamily C member 5provided by VGNC
Primary source
VGNC:VGNC:36385
See related
BGD:BT12543; Ensembl:ENSBTAG00000010065
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
trp
Orthologs
human mouse all
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Genomic context

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See TRPC5 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (59966892..60322797, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylglucosamine transferase subunit ALG13 homolog Neighboring gene putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 Neighboring gene TRPC5 opposite strand Neighboring gene retrotransposon Gag like 4 Neighboring gene uncharacterized LOC132344287 Neighboring gene LHFPL tetraspan subfamily member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nitric oxide activates TRP channels by cysteine S-nitrosylation. Yoshida T, et al. Nat Chem Biol, 2006 Nov. PMID 16998480
  2. Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells. Wong CO, et al. Pflugers Arch, 2010 Jun. PMID 20390293, Free PMC Article
  3. TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells. Philipp S, et al. J Biol Chem, 2000 Aug 4. PMID 10816590
  4. Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement. Chaudhuri P, et al. Mol Biol Cell, 2008 Aug. PMID 18495872, Free PMC Article
  5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nitrix oxide can negatively modulate endogenous TRPC5-containing channels through an indirect mechanism.
    Title: Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells.
  2. analysis of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement
    Title: Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol 1,4,5 trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables store-operated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in manganese ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cation channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
short transient receptor potential channel 5
Names
transient receptor potential channel 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166574.1 → NP_001160046.1  short transient receptor potential channel 5

    See identical proteins and their annotated locations for NP_001160046.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000030
    UniProtKB/TrEMBL
    F1MTE6
    Related
    ENSBTAP00000013270.4, ENSBTAT00000013270.6
    Conserved Domains (2) summary
    TIGR00870
    Location:17 → 756
    trp; transient-receptor-potential calcium channel protein
    sd00045
    Location:35 → 67
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    59966892..60322797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059883295.1 → XP_059739278.1  short transient receptor potential channel 5 isoform X1

    UniProtKB/TrEMBL
    F1MTE6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9MYV9.1 GenPept UniProtKB/Swiss-Prot:Q9MYV9

Gene LinkOut

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