U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ube2v2 ubiquitin-conjugating enzyme E2 variant 2 [ Danio rerio (zebrafish) ]

Gene ID: 406836, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
ube2v2provided by ZNC
Official Full Name
ubiquitin-conjugating enzyme E2 variant 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2919
See related
Ensembl:ENSDARG00000028198 AllianceGenome:ZFIN:ZDB-GENE-040426-2919
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63717; wu:fb18b11; wu:fb24d11
Summary
Acts upstream of or within protein K63-linked ubiquitination. Predicted to be active in nucleus. Orthologous to human UBE2V2 (ubiquitin conjugating enzyme E2 V2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ube2v2 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (35522298..35534273, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (35634201..35646176, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene syntrophin, gamma 1 Neighboring gene uncharacterized LOC108181546 Neighboring gene snail family zinc finger 2 Neighboring gene minichromosome maintenance complex component 4 Neighboring gene CCAAT enhancer binding protein delta

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The syntenic relationship of the zebrafish and human genomes. Barbazuk WB, et al. Genome Res, 2000 Sep. PMID 10984453, Free PMC Article
  2. An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX. Long MJC, et al. Acc Chem Res, 2021 Feb 2. PMID 33228351
  3. Zebrafish Ubc13 is required for Lys63-linked polyubiquitination and DNA damage tolerance. Li J, et al. Mol Cell Biochem, 2010 Oct. PMID 20556485
  4. Zebrafish Mms2 promotes K63-linked polyubiquitination and is involved in p53-mediated DNA-damage response. Wen R, et al. DNA Repair (Amst), 2012 Feb 1. PMID 22055568
  5. Differential gene expression and biomarkers in zebrafish (Danio rerio) following exposure to produced water components. Holth TF, et al. Aquat Toxicol, 2008 Dec 11. PMID 18963085

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in postreplication repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein K63-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein K63-linked ubiquitination IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ubiquitin conjugating enzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin-conjugating enzyme E2 variant 2
Names
Drmms2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213515.1 → NP_998680.1  ubiquitin-conjugating enzyme E2 variant 2

    See identical proteins and their annotated locations for NP_998680.1

    Status: PROVISIONAL

    Source sequence(s)
    BC058061
    UniProtKB/Swiss-Prot
    Q6PEH5
    Related
    ENSDARP00000004795.7, ENSDART00000026578.8
    Conserved Domains (1) summary
    smart00212
    Location:14 → 143
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic domain homologues

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    35522298..35534273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PEH5.1 GenPept UniProtKB/Swiss-Prot:Q6PEH5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.