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Hcs - Holocarboxylase synthetase

Enables biotin--[biotin carboxyl-carrier protein] ligase activity. Involved in chromatin organization and regulation of DNA-templated transcription. Is active in nucleus. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in holocarboxylase synthetase deficiency. Orthologous to human HLCS (holocarboxylase synthetase). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa