U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nipa2 NIPA magnesium transporter 2 [ Danio rerio (zebrafish) ]

Gene ID: 406399, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
nipa2provided by ZNC
Official Full Name
NIPA magnesium transporter 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2134
See related
Ensembl:ENSDARG00000055912 AllianceGenome:ZFIN:ZDB-GENE-040426-2134
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb72g02; zgc:66088; wu:fb72g02
Summary
Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be active in membrane. Is expressed in dorsal telencephalon and female organism. Orthologous to human NIPA2 (NIPA magnesium transporter 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See nipa2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (37733597..37745508, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (37755703..37767614, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene tubulin gamma complex component 5 Neighboring gene cytoplasmic FMR1 interacting protein 1 Neighboring gene fibronectin type III domain containing 9 Neighboring gene NIPA magnesium transporter 1 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Comparison between Timelines of Transcriptional Regulation in Mammals, Birds, and Teleost Fish Somitogenesis. Fongang B, et al. PLoS One, 2016. PMID 27192554, Free PMC Article
  2. Recent assembly of an imprinted domain from non-imprinted components. Rapkins RW, et al. PLoS Genet, 2006 Oct. PMID 17069464, Free PMC Article
  3. Asymmetric distribution of pallial-expressed genes in zebrafish (Danio rerio). Messina A, et al. Eur J Neurosci, 2021 Jan. PMID 32692463
  4. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Newman M, et al. Mol Brain, 2019 May 3. PMID 31053140, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables magnesium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in magnesium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within magnesium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
magnesium transporter NIPA2
Names
non imprinted in Prader-Willi/Angelman syndrome 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270536.1 → NP_001257465.1  magnesium transporter NIPA2

    See identical proteins and their annotated locations for NP_001257465.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    EB785012, EH457110, EH488048, EH575890
    UniProtKB/TrEMBL
    A0A8M1PGD1, Q6P694
    Conserved Domains (1) summary
    pfam05653
    Location:8 → 302
    Mg_trans_NIPA; Magnesium transporter NIPA

  2. NM_213125.2 → NP_998290.1  magnesium transporter NIPA2

    See identical proteins and their annotated locations for NP_998290.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    DT074263, EH488048, EH575890, FP085470
    UniProtKB/TrEMBL
    A0A8M1PGD1, Q6P694
    Related
    ENSDARP00000072778.3, ENSDART00000078316.5
    Conserved Domains (1) summary
    pfam05653
    Location:8 → 302
    Mg_trans_NIPA; Magnesium transporter NIPA

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    37733597..37745508 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165976.2 → XP_005166033.1  magnesium transporter NIPA2 isoform X2

    See identical proteins and their annotated locations for XP_005166033.1

    UniProtKB/TrEMBL
    A0A8M1PGD1, Q6P694
    Conserved Domains (1) summary
    pfam05653
    Location:8 → 302
    Mg_trans_NIPA; Magnesium transporter NIPA

  2. XM_005165975.5 → XP_005166032.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BDB1
    Conserved Domains (1) summary
    pfam05653
    Location:57 → 351
    Mg_trans_NIPA; Magnesium transporter NIPA
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools