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abce1 ATP-binding cassette, sub-family E (OABP), member 1 [ Danio rerio (zebrafish) ]

Gene ID: 406324, updated on 28-Oct-2024

Summary

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Official Symbol
abce1provided by ZNC
Official Full Name
ATP-binding cassette, sub-family E (OABP), member 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1995
See related
Ensembl:ENSDARG00000007216 AllianceGenome:ZFIN:ZDB-GENE-040426-1995
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56045; wu:fb34c09; wu:fe47b01; wu:fi09g07; zgc:111906
Summary
Predicted to enable ATP binding activity; iron ion binding activity; and ribosomal small subunit binding activity. Predicted to be involved in translational initiation and translational termination. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; head; intermediate cell mass of mesoderm; optic tectum; and ventral mesoderm. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to human ABCE1 (ATP binding cassette subfamily E member 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See abce1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (43695594..43718061, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (43894076..43916543, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 10 member 7 Neighboring gene OTU deubiquitinase 4 Neighboring gene anaphase promoting complex subunit 10 Neighboring gene uncharacterized LOC101884517

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia. Wan Y, et al. BMC Med Genomics, 2016 Mar 9. PMID 26961822, Free PMC Article
  2. Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Ferrante MI, et al. Hum Mol Genet, 2009 Jan 15. PMID 18971206, Free PMC Article
  3. Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. Zheng W, et al. PLoS One, 2014. PMID 24633177, Free PMC Article
  4. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Annilo T, et al. Genomics, 2006 Jul. PMID 16631343
  5. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Dean M, et al. Annu Rev Genomics Hum Genet, 2005. PMID 16124856

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC56045

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables ribosomal small subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational termination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ATP-binding cassette sub-family E member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213051.2 → NP_998216.2  ATP-binding cassette sub-family E member 1

    See identical proteins and their annotated locations for NP_998216.2

    Status: VALIDATED

    Source sequence(s)
    CT630191, CT660911, EH436341, EH443969, EH462331
    UniProtKB/TrEMBL
    A0A8M1PG70, Q6TNW3
    Related
    ENSDARP00000011642.7, ENSDART00000015777.8
    Conserved Domains (5) summary
    cd03236
    Location:78 → 332
    ABC_RNaseL_inhibitor_domain1; The ATP-binding cassette domain 1 of RNase L inhibitor
    cd03237
    Location:348 → 592
    ABC_RNaseL_inhibitor_domain2; The ATP-binding cassette domain 2 of RNase L inhibitor
    COG1245
    Location:4 → 597
    Rli1; Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis]
    pfam00037
    Location:48 → 71
    Fer4; 4Fe-4S binding domain
    pfam04068
    Location:6 → 37
    RLI; Possible Fer4-like domain in RNase L inhibitor, RLI

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    43695594..43718061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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