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Enoph Enolase-phosphatase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40630, updated on 10-May-2024

Summary

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Official Symbol
Enophprovided by FlyBase
Official Full Name
Enolase-phosphataseprovided by FlyBase
Primary source
FLYBASE:FBgn0037305
Locus tag
Dmel_CG12173
See related
AllianceGenome:FB:FBgn0037305
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
24644163; CG12173; Dmel\CG12173; ENOPH
Summary
Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Orthologous to human ENOPH1 (enolase-phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Enoph in Genome Data Viewer
Location:
82F7-82F7; 3-47.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5255444..5256681, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1081166..1082403, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cathepsin F Neighboring gene antisense RNA:CR44019 Neighboring gene uncharacterized protein Neighboring gene Tim17a2 Neighboring gene HIF prolyl hydroxylase Neighboring gene long non-coding RNA:CR45793

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng). Liu QX, et al. J Ginseng Res, 2018 Jul. PMID 29983616, Free PMC Article
  2. Abdominal-B neurons control Drosophila virgin female receptivity. Bussell JJ, et al. Curr Biol, 2014 Jul 21. PMID 24998527, Free PMC Article
  3. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
  4. A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses. Dubruille R, et al. PLoS Genet, 2009 Dec. PMID 20041201, Free PMC Article
  5. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acireductone synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acireductone synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-methionine salvage from methylthioadenosine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-methionine salvage from methylthioadenosine IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Enolase-phosphatase
Names
CG12173-PA
Enoph-PA
NP_649523.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5255444..5256681 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141266.3 → NP_649523.1  Enolase-phosphatase [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649523.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4V3F1, Q9VN95
    UniProtKB/TrEMBL
    Q4V565
    Related
    FBpp0078463
    Conserved Domains (2) summary
    TIGR01691
    Location:8 → 244
    enolase-ppase; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
    pfam13419
    Location:11 → 217
    HAD_2; Haloacid dehalogenase-like hydrolase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VN95.2 Q9VN95

Gene LinkOut

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