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s100a10b S100 calcium binding protein A10b [ Danio rerio (zebrafish) ]

Gene ID: 406276, updated on 28-Oct-2024

Summary

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Official Symbol
s100a10bprovided by ZNC
Official Full Name
S100 calcium binding protein A10bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1937
See related
Ensembl:ENSDARG00000025254 AllianceGenome:ZFIN:ZDB-GENE-040426-1937
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56142; wu:fa94d11; wu:fb05h04; hm:zehn1116
Summary
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including digestive system; ectoderm; hematopoietic system; lens; and solid lens vesicle. Orthologous to human S100A10 (S100 calcium binding protein A10). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See s100a10b in Genome Data Viewer
Location:
chromosome: 16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (23397785..23399285)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (23482753..23484253)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 46a Neighboring gene keratinocyte associated protein 2 Neighboring gene S100 calcium binding protein W Neighboring gene ictacalcin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An adult zebrafish model for adherent-invasive Escherichia coli indicates protection from AIEC infection by probiotic E. coli Nissle. Nag D, et al. iScience, 2022 Jul 15. PMID 35769878, Free PMC Article
  2. Using a zebrafish model to understand adherent-invasive Escherichia coli infection. Nag D, et al. STAR Protoc, 2022 Dec 16. PMID 36386878, Free PMC Article
  3. Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish. Gioacchino E, et al. Blood Adv, 2021 Jul 13. PMID 34170285, Free PMC Article
  4. Structural and functional diversification in the teleost S100 family of calcium-binding proteins. Kraemer AM, et al. BMC Evol Biol, 2008 Feb 14. PMID 18275604, Free PMC Article
  5. Transcriptomic responses of S100 family to bacterial and viral infection in zebrafish. Zhang C, et al. Fish Shellfish Immunol, 2019 Nov. PMID 31546038

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein S100-A10b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213003.1 → NP_998168.1  protein S100-A10b

    See identical proteins and their annotated locations for NP_998168.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045941
    UniProtKB/TrEMBL
    B2GNG5, F8W3E5, Q7ZVA4
    Related
    ENSDARP00000124401.1, ENSDART00000148961.2
    Conserved Domains (2) summary
    cd05031
    Location:3 → 96
    S-100A10_like; S-100A10_like: S-100A10 domain found in proteins similar to S100A10. S100A10 is a member of the S100 family of EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which this S-100A1_like group belongs, contains only S-100 ...
    pfam13499
    Location:25 → 79
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    23397785..23399285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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