chst14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: chst14provided by ZNC
Official Full Name: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14provided by ZNC
Primary source: ZFIN:ZDB-GENE-040401-3
See related: Ensembl:ENSDARG00000043011 AllianceGenome:ZFIN:ZDB-GENE-040401-3
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: d4st1; wu:fc04a01; zgc:136487
Summary: Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within carbohydrate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Is expressed in head; midbrain hindbrain boundary; notochord; pectoral fin; and spinal cord. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (25739979..25748311, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (25840889..25849221, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fc04a01.x1 (e-PCR)
- UniSTS:192148

fc04a01.x1 (e-PCR)
- UniSTS:192149

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables N-acetylgalactosamine 4-O-sulfotransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in dermatan sulfate proteoglycan metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dermatan sulfate proteoglycan metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carbohydrate sulfotransferase 14

Names: D4ST-1; dermatan 4-sulfotransferase 1; zD4ST-1

NP_997994.1

EC 2.8.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.