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BMPR1A bone morphogenetic protein receptor type 1A [ Bos taurus (domestic cattle) ]

Gene ID: 404101, updated on 4-Oct-2024

Summary

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Official Symbol
BMPR1Aprovided by VGNC
Official Full Name
bone morphogenetic protein receptor type 1Aprovided by VGNC
Primary source
VGNC:VGNC:26524
See related
BGD:BT10028; Ensembl:ENSBTAG00000000231
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
BMPR-IA
Orthologs
human mouse all
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Genomic context

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See BMPR1A in Genome Data Viewer
Location:
chromosome: 28
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (41403870..41545706)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene opsin 4 Neighboring gene LIM domain binding 3 Neighboring gene multimerin 2 Neighboring gene synuclein gamma

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development. Fatehi AN, et al. Theriogenology, 2005 Feb. PMID 15629804
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bone morphogenetic protein receptor type-1A
Names
bone morphogenetic protein receptor IA
bone morphogenetic protein receptor, type IA
NP_001070268.1
XP_005226588.1
XP_024842344.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076800.1 → NP_001070268.1  bone morphogenetic protein receptor type-1A precursor

    See identical proteins and their annotated locations for NP_001070268.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ922946
    UniProtKB/TrEMBL
    A0AAA9SHJ0, Q06AL7
    Related
    ENSBTAP00000000282.5, ENSBTAT00000000282.6
    Conserved Domains (3) summary
    smart00221
    Location:234 → 521
    STYKc; Protein kinase; unclassified specificity
    cd14220
    Location:238 → 524
    STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
    pfam01064
    Location:59 → 138
    Activin_recp; Activin types I and II receptor domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    41403870..41545706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005226531.5 → XP_005226588.1  bone morphogenetic protein receptor type-1A isoform X1

    See identical proteins and their annotated locations for XP_005226588.1

    UniProtKB/TrEMBL
    A0AAA9SHJ0, F1MCE7
    Conserved Domains (2) summary
    cd14220
    Location:238 → 524
    STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
    pfam01064
    Location:59 → 132
    Activin_recp; Activin types I and II receptor domain

  2. XM_024986576.2 → XP_024842344.1  bone morphogenetic protein receptor type-1A isoform X2

    UniProtKB/TrEMBL
    A0AAA9SHJ0
    Conserved Domains (2) summary
    cd14220
    Location:204 → 490
    STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
    pfam01064
    Location:25 → 98
    Activin_recp; Activin types I and II receptor domain
Nucleotide Protein Strain
Heading Accession and Version

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