PLA2G1B phospholipase A2 group IB [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PLA2G1Bprovided by VGNC
Official Full Name: phospholipase A2 group IBprovided by VGNC
Primary source: VGNC:VGNC:44622
See related: Ensembl:ENSCAFG00845029696
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 26

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	26	NC_051830.1 (16515905..16524689, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	26	NC_006608.4 (16252273..16261019, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	26	NC_049247.1 (16594969..16603767, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	26	NC_049286.1 (16476786..16485567, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	26	NC_049767.1 (16553497..16562238, complement)

Chromosome 26 - NC_051830.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cytosolic phospholipase A2 regulates lipid homeostasis under osmotic stress through PPARgamma.
Title: Cytosolic phospholipase A(2) regulates lipid homeostasis under osmotic stress through PPARγ.

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General gene information

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Markers

PLA2G1B (e-PCR)
- UniSTS:264153

PLA2G1B (e-PCR)
- UniSTS:258301

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium-dependent phospholipase A2 activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phospholipid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in arachidonate secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lipid catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phospholipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of fibroblast proliferation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phospholipase A2

Names: group IB phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2, group IB (pancreas)

NP_001003320.1

EC 3.1.1.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.