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IAPP islet amyloid polypeptide [ Canis lupus familiaris (dog) ]

Gene ID: 403909, updated on 17-Aug-2024

Summary

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Official Symbol
IAPPprovided by VGNC
Official Full Name
islet amyloid polypeptideprovided by VGNC
Primary source
VGNC:VGNC:41848
See related
Ensembl:ENSCAFG00845015514
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See IAPP in Genome Data Viewer
Location:
chromosome: 27
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (26621265..26625751, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (20156535..20161021)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (19861411..19865898)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (26484470..26488955, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (26462824..26467310, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092876 Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene GTP:AMP phosphotransferase AK3, mitochondrial-like Neighboring gene solute carrier organic anion transporter family member 1A2 Neighboring gene uncharacterized LOC119866417 Neighboring gene solute carrier organic anion transporter family member 1B2 Neighboring gene prefoldin subunit 4-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Canine IAPP cDNA sequence provides important clues regarding diabetogenesis and amyloidogenesis in type 2 diabetes. Jordan K, et al. Biochem Biophys Res Commun, 1990 Jun 15. PMID 2192709
  2. Nucleotide sequence of a cDNA for canine amylin. Albrandt K, et al. Biochim Biophys Acta, 1992 Feb 28. PMID 1543754
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
islet amyloid polypeptide
Names
amylin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003233.2 → NP_001003233.1  islet amyloid polypeptide precursor

    See identical proteins and their annotated locations for NP_001003233.1

    Status: PROVISIONAL

    Source sequence(s)
    X59998
    UniProtKB/Swiss-Prot
    P17716
    UniProtKB/TrEMBL
    A0A8C0QX88
    Related
    ENSCAFP00845021778.1, ENSCAFT00845027673.1
    Conserved Domains (1) summary
    pfam00214
    Location:27 → 73
    Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    26621265..26625751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    26484470..26488955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    26462824..26467310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    19861411..19865898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20156535..20161021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P17716.2 GenPept UniProtKB/Swiss-Prot:P17716

Gene LinkOut

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