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MX2 MX dynamin like GTPase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 403744, updated on 17-Aug-2024

Summary

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Official Symbol
MX2provided by VGNC
Official Full Name
MX dynamin like GTPase 2provided by VGNC
Primary source
VGNC:VGNC:43512
See related
Ensembl:ENSCAFG00845030104
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human all
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Genomic context

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See MX2 in Genome Data Viewer
Location:
chromosome: 31
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 31 NC_051835.1 (35368501..35400678)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 31 NC_006613.4 (35005886..35038055)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 31 NC_049252.1 (35736514..35768675)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 31 NC_049291.1 (35264320..35296463)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 31 NC_049772.1 (35242367..35274518)

Chromosome 31 - NC_051835.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867074 Neighboring gene uncharacterized LOC102153613 Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene MX dynamin like GTPase 1 Neighboring gene transmembrane serine protease 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intracellular localization and antiviral property of canine Mx proteins. Nakamura T, et al. J Interferon Cytokine Res, 2005 Mar. PMID 15767791
  2. Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis. Cao Z, et al. Mol Cell Proteomics, 2008 Sep. PMID 18504258, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon-induced GTP-binding protein Mx2
Names
GTP-binding protein Mx2
myxovirus resistance protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051835.1 Reference ROS_Cfam_1.0

    Range
    35368501..35400678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038443558.1 → XP_038299486.1  interferon-induced GTP-binding protein Mx2 isoform X1

    UniProtKB/Swiss-Prot
    Q9N0Y2
    UniProtKB/TrEMBL
    A0A8C0P6N8
    Related
    ENSCAFP00845041949.1, ENSCAFT00845053398.1
    Conserved Domains (3) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region
    pfam02212
    Location:621 → 709
    GED; Dynamin GTPase effector domain

  2. XM_038443559.1 → XP_038299487.1  interferon-induced GTP-binding protein Mx2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P6N8
    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region

  3. XM_038443560.1 → XP_038299488.1  interferon-induced GTP-binding protein Mx2 isoform X3

    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 522
    Dynamin_M; Dynamin central region

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049291.1 Alternate UMICH_Zoey_3.1

    Range
    35264320..35296463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038517969.1 → XP_038373897.1  interferon-induced GTP-binding protein Mx2 isoform X1

    Conserved Domains (3) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region
    pfam02212
    Location:621 → 709
    GED; Dynamin GTPase effector domain

  2. XM_038517970.1 → XP_038373898.1  interferon-induced GTP-binding protein Mx2 isoform X2

    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region

  3. XM_038517971.1 → XP_038373899.1  interferon-induced GTP-binding protein Mx2 isoform X3

    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 522
    Dynamin_M; Dynamin central region

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049772.1 Alternate UNSW_CanFamBas_1.0

    Range
    35242367..35274518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038645923.1 → XP_038501851.1  interferon-induced GTP-binding protein Mx2 isoform X1

  2. XM_038645924.1 → XP_038501852.1  interferon-induced GTP-binding protein Mx2 isoform X2

  3. XM_038645925.1 → XP_038501853.1  interferon-induced GTP-binding protein Mx2 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049252.1 Alternate UU_Cfam_GSD_1.0

    Range
    35736514..35768675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038581537.1 → XP_038437465.1  interferon-induced GTP-binding protein Mx2 isoform X1

    UniProtKB/Swiss-Prot
    Q9N0Y2
    UniProtKB/TrEMBL
    A0A8C0P6N8
    Conserved Domains (3) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region
    pfam02212
    Location:621 → 709
    GED; Dynamin GTPase effector domain

  2. XM_038581538.1 → XP_038437466.1  interferon-induced GTP-binding protein Mx2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P6N8
    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region

  3. XM_038581539.1 → XP_038437467.1  interferon-induced GTP-binding protein Mx2 isoform X3

    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 522
    Dynamin_M; Dynamin central region

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35005886..35038055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038461822.1 → XP_038317750.1  interferon-induced GTP-binding protein Mx2 isoform X1

    UniProtKB/Swiss-Prot
    Q9N0Y2
    UniProtKB/TrEMBL
    A0A8C0P6N8
    Conserved Domains (3) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region
    pfam02212
    Location:621 → 709
    GED; Dynamin GTPase effector domain

  2. XM_038461823.1 → XP_038317751.1  interferon-induced GTP-binding protein Mx2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P6N8
    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 594
    Dynamin_M; Dynamin central region

  3. XM_038461824.1 → XP_038317752.1  interferon-induced GTP-binding protein Mx2 isoform X3

    Conserved Domains (2) summary
    cd08771
    Location:116 → 387
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:307 → 522
    Dynamin_M; Dynamin central region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001003133.1: Suppressed sequence

    Description
    NM_001003133.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N0Y2.1 GenPept UniProtKB/Swiss-Prot:Q9N0Y2

Gene LinkOut

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