YBX3 Y-box binding protein 3 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: YBX3provided by VGNC
Official Full Name: Y-box binding protein 3provided by VGNC
Primary source: VGNC:VGNC:48480
See related: Ensembl:ENSCAFG00845025328
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: CSDA; dpbA; ZONAB
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	27	NC_051831.1 (35383798..35411218)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	27	NC_006609.4 (11465924..11493283, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	27	NC_049248.1 (11081610..11108979, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	27	NC_049287.1 (35266703..35294044)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	27	NC_049768.1 (35211037..35238385)

Chromosome 27 - NC_051831.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

examined the localization and activity of DbpA and YAP in Madin-Darby canine kidney cells depleted either of ZO-1, or one of the related proteins ZO-2 and ZO-3 (ZO proteins), or all three together
Title: ZO proteins redundantly regulate the transcription factor DbpA/ZONAB.
data thus indicate that GEF-H1 and ZONAB form a signalling module that mediates Rho-regulated cyclin D1 promoter activation and expression.
Title: The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription.
Apg-2 regulates ZONAB function by competing for binding to the SH3 domain of ZO-1 and suggest that Apg-2 functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress.
Title: The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.
data presented here implicate the RalA/ZONAB interaction in the regulation of ZONAB function
Title: RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ha2919 (e-PCR)
- UniSTS:515610

IB391 (e-PCR)
- UniSTS:20001

CSDA (e-PCR), detects polymorphism
- UniSTS:266280

D16S2544E (e-PCR)
- UniSTS:151633

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of gene expression	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: Y-box-binding protein 3

Names: Y-box protein ZONAB-A; cold shock domain protein A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.