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ME1 malic enzyme 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403709, updated on 17-Aug-2024

Summary

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Official Symbol
ME1provided by VGNC
Official Full Name
malic enzyme 1provided by VGNC
Primary source
VGNC:VGNC:43109
See related
Ensembl:ENSCAFG00845011557
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ME1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (44390732..44586598, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (43436816..43632406, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (43840059..44036221, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (43730159..43925658, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (43679098..43858889, complement)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene DOP1 leucine zipper like protein A Neighboring gene phosphoglucomutase 3 Neighboring gene RWD domain containing 2A Neighboring gene TATA box-binding protein-associated factor RNA polymerase I subunit D-like Neighboring gene acyl-protein thioesterase 1-like Neighboring gene uncharacterized LOC119874209

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyruvate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADP-dependent malic enzyme
Names
malic enzyme 1, NADP(+)-dependent, cytosolic
XP_038348273.1
XP_038348274.1
XP_038348275.1
XP_038410559.1
XP_038410560.1
XP_038410561.1
XP_038474423.1
XP_038474425.1
XP_038527876.1
XP_038527893.1
XP_038539982.1
XP_038539984.1
XP_038539985.1
XP_532217.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    44390732..44586598 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038684054.1 → XP_038539982.1  NADP-dependent malic enzyme isoform X2

    UniProtKB/TrEMBL
    A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73
    Related
    ENSCAFP00845016069.1, ENSCAFT00845020496.1
    Conserved Domains (1) summary
    PLN03129
    Location:14 → 551
    PLN03129; NADP-dependent malic enzyme; Provisional

  2. XM_038684057.1 → XP_038539985.1  NADP-dependent malic enzyme isoform X3

    UniProtKB/TrEMBL
    A0A8C0KSZ8
    Related
    ENSCAFP00845016155.1, ENSCAFT00845020597.1
    Conserved Domains (1) summary
    PLN03129
    Location:1 → 476
    PLN03129; NADP-dependent malic enzyme; Provisional

  3. XM_038684056.1 → XP_038539984.1  NADP-dependent malic enzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSZ8, A0A8P0ST92
    Conserved Domains (1) summary
    PLN03129
    Location:2 → 526
    PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    43730159..43925658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038492345.1 → XP_038348273.1  NADP-dependent malic enzyme isoform X2

    Conserved Domains (1) summary
    PLN03129
    Location:14 → 551
    PLN03129; NADP-dependent malic enzyme; Provisional

  2. XM_038492347.1 → XP_038348275.1  NADP-dependent malic enzyme isoform X3

    Conserved Domains (1) summary
    PLN03129
    Location:1 → 476
    PLN03129; NADP-dependent malic enzyme; Provisional

  3. XM_038492346.1 → XP_038348274.1  NADP-dependent malic enzyme isoform X1

    Conserved Domains (1) summary
    PLN03129
    Location:2 → 526
    PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    43679098..43858889 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038618495.1 → XP_038474423.1  NADP-dependent malic enzyme isoform X2

    Conserved Domains (1) summary
    PLN03129
    Location:14 → 551
    PLN03129; NADP-dependent malic enzyme; Provisional

  2. XM_038618497.1 → XP_038474425.1  NADP-dependent malic enzyme isoform X3

    Conserved Domains (1) summary
    PLN03129
    Location:1 → 476
    PLN03129; NADP-dependent malic enzyme; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    43840059..44036221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554631.1 → XP_038410559.1  NADP-dependent malic enzyme isoform X2

    UniProtKB/TrEMBL
    A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73
    Conserved Domains (1) summary
    PLN03129
    Location:14 → 551
    PLN03129; NADP-dependent malic enzyme; Provisional

  2. XM_038554633.1 → XP_038410561.1  NADP-dependent malic enzyme isoform X3

    UniProtKB/TrEMBL
    A0A8C0KSZ8
    Conserved Domains (1) summary
    PLN03129
    Location:1 → 476
    PLN03129; NADP-dependent malic enzyme; Provisional

  3. XM_038554632.1 → XP_038410560.1  NADP-dependent malic enzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSZ8, A0A8P0ST92
    Conserved Domains (1) summary
    PLN03129
    Location:2 → 526
    PLN03129; NADP-dependent malic enzyme; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    43436816..43632406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671948.1 → XP_038527876.1  NADP-dependent malic enzyme isoform X2

    UniProtKB/TrEMBL
    A0A8C0MKN3, A0A8I3NIY1, A0A8I3NJ10, A0A8P0SP73
    Conserved Domains (1) summary
    PLN03129
    Location:14 → 551
    PLN03129; NADP-dependent malic enzyme; Provisional

  2. XM_038671965.1 → XP_038527893.1  NADP-dependent malic enzyme isoform X3

    UniProtKB/TrEMBL
    A0A8C0KSZ8
    Conserved Domains (1) summary
    PLN03129
    Location:1 → 476
    PLN03129; NADP-dependent malic enzyme; Provisional

  3. XM_532217.6 → XP_532217.4  NADP-dependent malic enzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0KSZ8, A0A8P0ST92
    Conserved Domains (1) summary
    PLN03129
    Location:2 → 526
    PLN03129; NADP-dependent malic enzyme; Provisional
Nucleotide Protein
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