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Edg78E Ecdysone-dependent gene 78E [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40354, updated on 18-Sep-2024

Summary

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Official Symbol
Edg78Eprovided by FlyBase
Official Full Name
Ecdysone-dependent gene 78Eprovided by FlyBase
Primary source
FLYBASE:FBgn0000551
Locus tag
Dmel_CG7673
See related
AllianceGenome:FB:FBgn0000551
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7673; DmelEdg78E; Dmel\CG7673; DMLCP78; EDG-78; Edg78; EDG78; Edg78e; EDG78E
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. Is expressed in epidermis. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Edg78E in Genome Data Viewer
Location:
78C6-78C6; 3-47 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21296763..21297803, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21289863..21290903, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 78Ca Neighboring gene Cuticular protein 78Cb Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 78Cc

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BetaFTZ-F1 dependent and independent activation of Edg78E, a pupal cuticle gene, during the early metamorphic period in Drosophila melanogaster. Kawasaki H, et al. Dev Growth Differ, 2002 Oct. PMID 12392575
  2. 20-Hydroxyecdysone is required for, and negatively regulates, transcription of Drosophila pupal cuticle protein genes. Apple RT, et al. Dev Biol, 1991 Aug. PMID 1713868
  3. Evolution of the Drosophila broad locus: the Manduca sexta broad Z4 isoform has biological activity in Drosophila. Bayer C, et al. Dev Genes Evol, 2003 Oct. PMID 13680224
  4. Prepupal differentiation in Drosophila: distinct cell types elaborate a shared structure, the pupal cuticle, but accumulate transcripts in unique patterns. Fechtel K, et al. Development, 1989 Aug. PMID 2562660
  5. Prepupal differentiation of Drosophila imaginal discs: identification of four genes whose transcripts accumulate in response to a pulse of 20-hydroxyecdysone. Fechtel K, et al. Genetics, 1988 Oct. PMID 2461886, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
enables structural constituent of pupal chitin-based cuticle TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Ecdysone-dependent gene 78E
Names
CG7673-PA
CG7673-PB
Edg78E-PA
Edg78E-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21296763..21297803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079474.3 → NP_524198.1  Ecdysone-dependent gene 78E, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524198.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P27779, Q9VP54
    UniProtKB/TrEMBL
    D4G7H0, X2JGZ5
    Related
    FBpp0078062
    Conserved Domains (1) summary
    pfam00379
    Location:39 → 85
    Chitin_bind_4; Insect cuticle protein

  2. NM_001300211.1 → NP_001287140.1  Ecdysone-dependent gene 78E, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287140.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P27779, Q9VP54
    UniProtKB/TrEMBL
    D4G7H0, X2JGZ5
    Conserved Domains (1) summary
    pfam00379
    Location:39 → 85
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P27779.1 P27779
X2JGZ5 X2JGZ5

Gene LinkOut

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