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slc5a8.L solute carrier family 5 member 8, gene 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 403396, updated on 4-Nov-2024

Summary

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Official Symbol
slc5a8.L
Official Full Name
solute carrier family 5 member 8, gene 1 L homeolog
Primary source
Xenbase:XB-GENE-865289
Locus tag
XELAEV_18017365mg
See related
EnsemblRapid:ENSXLAG00005005845 AllianceGenome:Xenbase:XB-GENE-865289
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
vito; smct1; smcte; slc5a8.1; slc5a8.1.L
Summary
Predicted to enable monocarboxylate:sodium symporter activity. Predicted to act upstream of or within monoatomic anion transport; monocarboxylic acid transport; and nitrate transmembrane transport. Predicted to be located in apical plasma membrane and extracellular exosome. Is expressed in ectoderm; endoderm; mesoderm; and urinary system. Orthologous to human SLC5A8 (solute carrier family 5 member 8). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See slc5a8.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (56007099..56025918, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (41555998..41574787, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121401482 Neighboring gene anoctamin 4 L homeolog Neighboring gene sodium-coupled monocarboxylate transporter 1-like Neighboring gene UTP20 small subunit processome component L homeolog Neighboring gene U6 spliceosomal RNA Neighboring gene ARF like GTPase 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel gene expression domains reveal early patterning of the Xenopus endoderm. Costa RM, et al. Gene Expr Patterns, 2003 Aug. PMID 12915320
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables monocarboxylate:sodium symporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables organic acid:sodium symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within acetate transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within chloride transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within iodide transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within lactate transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within nicotinate transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within nitrate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within propanoate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within propanoate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within pyruvate transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular exosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sodium-coupled monocarboxylate transporter 1
Names
electrogenic sodium monocarboxylate cotransporter
slc5a8
sodium solute transporter Vito
solute carrier family 5 (iodide transporter), member 8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 L homeolog
solute carrier family 5 member 8 L homeolog
xSMCTe

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090985.1 → NP_001084454.1  sodium-coupled monocarboxylate transporter 1

    See identical proteins and their annotated locations for NP_001084454.1

    Status: PROVISIONAL

    Source sequence(s)
    AY260728
    UniProtKB/Swiss-Prot
    Q6PAX9, Q7SYH3, Q7SYH4, Q7SYH5
    UniProtKB/TrEMBL
    A0A974DCA4
    Related
    ENSXLAP00005017411.1, ENSXLAT00005017708.1
    Conserved Domains (1) summary
    cd11519
    Location:7 → 549
    SLC5sbd_SMCT1; Na(+)/monocarboxylate cotransporter SMCT1 and related proteins; solute-binding domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    56007099..56025918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7SYH5.1 GenPept UniProtKB/Swiss-Prot:Q7SYH5

Gene LinkOut

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Molecular Biology Databases
Research Materials