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mmgt1 membrane magnesium transporter 1 [ Danio rerio (zebrafish) ]

Gene ID: 402891, updated on 2-Nov-2024

Summary

Official Symbol
mmgt1provided by ZNC
Official Full Name
membrane magnesium transporter 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-65
See related
Ensembl:ENSDARG00000010553 AllianceGenome:ZFIN:ZDB-GENE-040801-65
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tmem32; zgc:92918
Summary
Predicted to enable magnesium ion transmembrane transporter activity. Predicted to contribute to membrane insertase activity. Predicted to be involved in magnesium ion transport; protein insertion into ER membrane by stop-transfer membrane-anchor sequence; and tail-anchored membrane protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Predicted to be active in Golgi apparatus; early endosome; and plasma membrane. Orthologous to human MMGT1 (membrane magnesium transporter 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See mmgt1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (31615577..31618205, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (31275263..31277891, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene motile sperm domain containing 1 Neighboring gene integrator complex subunit 6 like Neighboring gene solute carrier family 9 member A6a Neighboring gene four and a half LIM domains 1a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables inorganic cation transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables magnesium ion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
contributes_to membrane insertase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in magnesium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein insertion into ER membrane by stop-transfer membrane-anchor sequence ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in tail-anchored membrane protein insertion into ER membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of EMC complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of EMC complex ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in early endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ER membrane protein complex subunit 5
Names
transmembrane protein 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205599.1NP_991162.1  ER membrane protein complex subunit 5

    See identical proteins and their annotated locations for NP_991162.1

    Status: PROVISIONAL

    Source sequence(s)
    AY394962
    UniProtKB/Swiss-Prot
    Q6TLE4
    Related
    ENSDARP00000005525.6, ENSDART00000016592.8
    Conserved Domains (1) summary
    pfam10270
    Location:2661
    MMgT; Membrane magnesium transporter

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    31615577..31618205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394915.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    171844..174442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)