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RhoBTB - Rho-related BTB domain containing

Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in melanotic encapsulation of foreign target. Predicted to be active in plasma membrane. Is expressed in several structures, including central brain primordium; dorsal epidermis primordium; embryonic dorsal epidermis; extraembryonic structure; and ganglia. Used to study developmental and epileptic encephalopathy 64. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 64. Orthologous to human RHOBTB1 (Rho related BTB domain containing 1) and RHOBTB2 (Rho related BTB domain containing 2). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa