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CG7365 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40200, updated on 18-Sep-2024

Summary

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Official Symbol
CG7365provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036939
Locus tag
Dmel_CG7365
See related
AllianceGenome:FB:FBgn0036939
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7365
Summary
Predicted to enable calcium-independent phospholipase A2 activity and lysophospholipase activity. Predicted to be involved in phospholipid metabolic process. Orthologous to human PLB1 (phospholipase B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG7365 in Genome Data Viewer
Location:
76F2-76F2; 3-46 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20124298..20127381, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20117398..20120481, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 76b Neighboring gene uncharacterized protein Neighboring gene gigas Neighboring gene obstructor-J Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis. Pandey V, et al. Front Cell Neurosci, 2013. PMID 24058333, Free PMC Article
  2. Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. Napoletano F, et al. EMBO J, 2011 Mar 2. PMID 21278706, Free PMC Article
  3. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article
  4. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
  5. Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. Palu RA, et al. PLoS Genet, 2016 Apr. PMID 27058248, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium-independent phospholipase A2 activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables lysophospholipase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phospholipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7365-PA
CG7365-PB
NP_001262088.1
NP_649178.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    20124298..20127381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140921.3 → NP_649178.1  uncharacterized protein Dmel_CG7365, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649178.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW80
    Related
    FBpp0074636
    Conserved Domains (1) summary
    cd01824
    Location:95 → 385
    Phospholipase_B_like; Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity. It's members may be involved in the conversion of phosphatidylcholine to fatty acids and ...

  2. NM_001275159.1 → NP_001262088.1  uncharacterized protein Dmel_CG7365, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262088.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW80
    Conserved Domains (1) summary
    cd01824
    Location:95 → 385
    Phospholipase_B_like; Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity. It's members may be involved in the conversion of phosphatidylcholine to fatty acids and ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VW80 Q9VW80

Gene LinkOut

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