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Usp32 Ubiquitin specific protease 32 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40169, updated on 28-Oct-2024

Summary

Official Symbol
Usp32provided by FlyBase
Official Full Name
Ubiquitin specific protease 32provided by FlyBase
Primary source
FLYBASE:FBgn0036913
Locus tag
Dmel_CG8334
See related
AllianceGenome:FB:FBgn0036913
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8334; Dmel\CG8334; dUSP15; Q9VW49; USP15; usp32
Summary
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to several human genes including USP32 (ubiquitin specific peptidase 32). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See Usp32 in Genome Data Viewer
Location:
76D3-76D3; 3-46 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19871139..19881783)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19864239..19874883)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45433 Neighboring gene Rab8 Neighboring gene Mi-2 Neighboring gene Suppressor of Triplolethal Neighboring gene long non-coding RNA:CR32218 Neighboring gene antisense RNA:CR43889

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ubiquitin specific protease 32
Names
CG8334-PF
CG8334-PG
CG8334-PH
CG8334-PI
Usp32-PF
Usp32-PG
Usp32-PH
Usp32-PI
NP_001262074.2
NP_001262075.2
NP_001262076.2
NP_001262077.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19871139..19881783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275145.2NP_001262074.2  ubiquitin specific protease 32, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PD06, M9PFQ1, M9PFZ0, M9PG46
    Conserved Domains (3) summary
    COG5126
    Location:186317
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    COG5560
    Location:4861002
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cl02553
    Location:14801737
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
  2. NM_001275148.2NP_001262077.2  ubiquitin specific protease 32, isoform I [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PD06, M9PFQ1, M9PFZ0, M9PG46
    Conserved Domains (3) summary
    COG5126
    Location:186317
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    COG5560
    Location:4861002
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cl02553
    Location:14771734
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
  3. NM_001275146.2NP_001262075.2  ubiquitin specific protease 32, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PD06, M9PFQ1, M9PFZ0, M9PG46
    Conserved Domains (3) summary
    COG5126
    Location:186317
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    COG5560
    Location:4861002
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cl02553
    Location:14611718
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
  4. NM_001275147.2NP_001262076.2  ubiquitin specific protease 32, isoform H [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PD06, M9PFQ1, M9PFZ0, M9PG46
    Conserved Domains (3) summary
    COG5126
    Location:186317
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    COG5560
    Location:4861002
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cl02553
    Location:14581715
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...