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Ccdc58 Coiled-coil domain-containing 58 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40159, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc58provided by FlyBase
Official Full Name
Coiled-coil domain-containing 58provided by FlyBase
Primary source
FLYBASE:FBgn0036909
Locus tag
Dmel_CG15881
See related
AllianceGenome:FB:FBgn0036909
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:HL01254; CG15881; Dmel\CG15881
Summary
Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Is expressed in several structures, including adult heart; anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and posterior endoderm. Orthologous to human MIX23 (mitochondrial matrix import factor 23). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See Ccdc58 in Genome Data Viewer
Location:
76C6-76C6; 3-46 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19805181..19806932)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19798281..19800032)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 76a Neighboring gene Torsin interacting protein Neighboring gene uncharacterized protein Neighboring gene karyopherin alpha1 Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 305a1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis. Ratan R, et al. Genetics, 2008 Feb. PMID 18245351, Free PMC Article
  2. Identification of critical host mitochondrion-associated genes during Ehrlichia chaffeensis infections. Von Ohlen T, et al. Infect Immun, 2012 Oct. PMID 22851751, Free PMC Article
  3. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article
  4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
  5. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Coiled-coil domain-containing 58
Names
CG15881-PA
CG15881-PB
CG15881-PC
Ccdc58-PA
Ccdc58-PB
Ccdc58-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19805181..19806932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140893.3 → NP_649150.1  Coiled-coil domain-containing 58, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649150.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KUT5
    Related
    FBpp0074648
    Conserved Domains (1) summary
    pfam09774
    Location:4 → 111
    Cid2; Caffeine-induced death protein 2

  2. NM_001300192.1 → NP_001287121.1  Coiled-coil domain-containing 58, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287121.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KUT5
    Conserved Domains (1) summary
    pfam09774
    Location:4 → 111
    Cid2; Caffeine-induced death protein 2

  3. NM_168819.3 → NP_730454.2  Coiled-coil domain-containing 58, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730454.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW41
    Related
    FBpp0074649
    Conserved Domains (1) summary
    pfam09774
    Location:5 → 128
    Cid2; Caffeine-induced death protein 2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KUT5 Q7KUT5
Q9VW41 Q9VW41

Gene LinkOut

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