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Cpr76Bd Cuticular protein 76Bd [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40123, updated on 18-Sep-2024

Summary

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Official Symbol
Cpr76Bdprovided by FlyBase
Official Full Name
Cuticular protein 76Bdprovided by FlyBase
Primary source
FLYBASE:FBgn0036881
Locus tag
Dmel_CG9299
See related
AllianceGenome:FB:FBgn0036881
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9299; DmelCpr76Bd; Dmel\CG9299
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in adult head. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Cpr76Bd in Genome Data Viewer
Location:
76B6-76B6; 3-45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19532743..19538289)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19525843..19531389)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 76Bb Neighboring gene Cuticular protein 76Bc Neighboring gene uncharacterized protein Neighboring gene Dctn1-related Neighboring gene antisense RNA:CR43885 Neighboring gene uncharacterized protein Neighboring gene Listerin E3 ubiquitin protein ligase 1 Neighboring gene Reduction in Cnn dots 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pluripotency and a secretion mechanism of Drosophila transglutaminase. Shibata T, et al. J Biochem, 2018 Mar 1. PMID 28992227
  2. Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila. Shibata T, et al. PLoS One, 2010 Oct 18. PMID 20976106, Free PMC Article
  3. Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. Cornman RS, et al. Insect Biochem Mol Biol, 2008 Jun. PMID 18510978, Free PMC Article
  4. How do Wolbachia modify the Drosophila ovary? New evidences support the "titration-restitution" model for the mechanisms of Wolbachia-induced CI. He Z, et al. BMC Genomics, 2019 Jul 24. PMID 31340757, Free PMC Article
  5. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cuticular protein 76Bd
Names
CG9299-PB
CG9299-PC
CG9299-PD
Cpr76Bd-PB
Cpr76Bd-PC
Cpr76Bd-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19532743..19538289
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275123.1 → NP_001262052.1  cuticular protein 76Bd, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262052.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PFX4
    Conserved Domains (1) summary
    pfam00379
    Location:1156 → 1208
    Chitin_bind_4; Insect cuticle protein

  2. NM_001104175.3 → NP_001097645.1  cuticular protein 76Bd, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097645.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW05
    Conserved Domains (1) summary
    pfam00379
    Location:1153 → 1205
    Chitin_bind_4; Insect cuticle protein

  3. NM_001275124.1 → NP_001262053.1  cuticular protein 76Bd, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW05
    Conserved Domains (1) summary
    pfam00379
    Location:1153 → 1205
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PFX4 M9PFX4
Q9VW05 Q9VW05

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