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LINC02245 long intergenic non-protein coding RNA 2245 [ Homo sapiens (human) ]

Gene ID: 400958, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02245provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2245provided by HGNC
Primary source
HGNC:HGNC:53134
See related
AllianceGenome:HGNC:53134
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
2p14
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (64901840..64932447, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (64911457..64942061, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (65128974..65159581, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 341, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65058033-65059232 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65065480-65066679 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15909 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15910 Neighboring gene long intergenic non-protein coding RNA 1800 Neighboring gene Sharpr-MPRA regulatory region 2197 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65087040-65087243 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15911 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11569 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65103167-65103373 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65131242-65131436 Neighboring gene Sharpr-MPRA regulatory region 15627 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15913 Neighboring gene RNA, 7SL, cytoplasmic 211, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15914 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15915 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15917 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15918 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15919 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:65165275-65165830 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15920 Neighboring gene ribosomal protein L11 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15921 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15922 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:65216535-65217119 Neighboring gene RNA, U6 small nuclear 548, pseudogene Neighboring gene solute carrier family 1 member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. lncRNAs as Novel Indicators of Patients' Prognosis in Stage I Epithelial Ovarian Cancer: A Retrospective and Multicentric Study. Martini P, et al. Clin Cancer Res, 2017 May 1. PMID 27827314
  2. Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c. Zhang Z, et al. Genet Test Mol Biomarkers, 2020 Feb. PMID 31999493
  3. Super-lncRNAs: identification of lncRNAs that target super-enhancers via RNA:DNA:DNA triplex formation. Soibam B. RNA, 2017 Nov. PMID 28839111, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c.
    Title: Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • lnc-SERTAD2-3

Clone Names

  • AC007386.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036586.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007386, BC037562

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    64901840..64932447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    64911457..64942061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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