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mRpL21 mitochondrial ribosomal protein L21 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40091, updated on 10-May-2024

Summary

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Official Symbol
mRpL21provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L21provided by FlyBase
Primary source
FLYBASE:FBgn0036853
Locus tag
Dmel_CG9730
See related
AllianceGenome:FB:FBgn0036853
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9730; Dmel\CG9730; MRP-L21
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL21 (mitochondrial ribosomal protein L21). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See mRpL21 in Genome Data Viewer
Location:
76A3-76A3; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19253290..19255061, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19246390..19248161, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43892 Neighboring gene long non-coding RNA:CR46216 Neighboring gene reptin Neighboring gene antisense RNA:CR45210 Neighboring gene nessy

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. Koc EC, et al. J Biol Chem, 2001 Nov 23. PMID 11551941
  2. Identification and Characterization of Breakpoints and Mutations on Drosophila melanogaster Balancer Chromosomes. Miller DE, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972999, Free PMC Article
  3. Toll mediated infection response is altered by gravity and spaceflight in Drosophila. Taylor K, et al. PLoS One, 2014. PMID 24475130, Free PMC Article
  4. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422
  5. The genetic makeup of the Drosophila piRNA pathway. Handler D, et al. Mol Cell, 2013 Jun 6. PMID 23665231, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
  
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial ribosomal protein L21
Names
CG9730-PA
CG9730-PB
CG9730-PC
mRpL21-PA
mRpL21-PB
mRpL21-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19253290..19255061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300183.1 → NP_001287112.1  mitochondrial ribosomal protein L21, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287112.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVX4
    Conserved Domains (1) summary
    pfam00829
    Location:85 → 175
    Ribosomal_L21p; Ribosomal prokaryotic L21 protein

  2. NM_001275110.1 → NP_001262039.1  mitochondrial ribosomal protein L21, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262039.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVX4
    Conserved Domains (1) summary
    pfam00829
    Location:85 → 175
    Ribosomal_L21p; Ribosomal prokaryotic L21 protein

  3. NM_140838.3 → NP_649095.2  mitochondrial ribosomal protein L21, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649095.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVX4
    Related
    FBpp0074789
    Conserved Domains (1) summary
    pfam00829
    Location:85 → 175
    Ribosomal_L21p; Ribosomal prokaryotic L21 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYD8 Q8SYD8
Q9VVX4 Q9VVX4

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