PRAMEF13 PRAME family member 13 [Homo sapiens (human)] - Gene

Summary

Official Symbol: PRAMEF13provided by HGNC
Official Full Name: PRAME family member 13provided by HGNC
Primary source: HGNC:HGNC:13262
See related: Ensembl:ENSG00000279169 AllianceGenome:HGNC:13262
Gene type: protein coding
RefSeq status: INFERRED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 1p36.21

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (13196188..13201409, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (12544302..12549523)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (13447414..13452656, complement)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

D1S2582 (e-PCR)
- UniSTS:35843

NoName (e-PCR)
- UniSTS:482354

RH102749 (e-PCR)
- UniSTS:97083

NoName (e-PCR)
- UniSTS:486825

NoName (e-PCR)
- UniSTS:481007

NoName (e-PCR)
- UniSTS:482548

Gene Ontology Provided by GOA

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative PRAME family member 13; PRAME family member-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001291380.1 → NP_001278309.1 putative PRAME family member 13

Status: INFERRED

Source sequence(s)

AC244216, AC245056

Consensus CDS

CCDS85927.1

UniProtKB/Swiss-Prot

Q5VWM6

UniProtKB/TrEMBL

B3KWQ4

Related

ENSP00000491259.1, ENST00000625019.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000001.11 Reference GRCh38.p14 Primary Assembly

Range

13196188..13201409 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011541458.1 → XP_011539760.1 PRAME family member-like isoform X1

UniProtKB/TrEMBL

A0A1W2PPB9, Q8IW67

Related

ENSP00000491071.1, ENST00000638454.1

Reference GRCh38.p14 PATCHES

Genomic

NW_012132914.1 Reference GRCh38.p14 PATCHES

Range

350528..355749 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331860.1 → XP_054187835.1 PRAME family member-like isoform X1

UniProtKB/TrEMBL

A0A1W2PPB9

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

NT_187517.1 Reference GRCh38.p14 ALT_REF_LOCI_1

Range

139647..144868 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054328622.1 → XP_054184597.1 PRAME family member-like isoform X1

Alternate T2T-CHM13v2.0

Genomic

NC_060925.1 Alternate T2T-CHM13v2.0

Range

12544302..12549523

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054336568.1 → XP_054192543.1 PRAME family member-like isoform X2
XM_054336569.1 → XP_054192544.1 PRAME family member-like isoform X3

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NG_005159.2: Suppressed sequence

Description

NG_005159.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.