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CG7430 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39988, updated on 18-Sep-2024

Summary

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Official Symbol
CG7430provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036762
Locus tag
Dmel_CG7430
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7430; E3
Orthologs
all
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Genomic context

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See CG7430 in Genome Data Viewer
Location:
75A4-75A4; 3-45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17846916..17849601)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17840016..17842701)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45175 Neighboring gene uncharacterized protein Neighboring gene Mediator complex subunit 19 Neighboring gene Tryptophanyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Friedman AA, et al. Sci Signal, 2011 Oct 25. PMID 22028469, Free PMC Article
  2. In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor. Baker FC, et al. Development, 2021 Nov 15. PMID 35020877, Free PMC Article
  3. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
  4. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article
  5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables dihydrolipoyl dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in 2-oxoglutarate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyruvate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of oxoglutarate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7430-PA
CG7430-PB
alpha-ketoglutarate dehydrogenase
alpha-ketoglutarate dehydrogenase E3 subunit
pyruvate dehydrogenase E3 subunit
NP_001262000.1
NP_649017.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17846916..17849601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140760.4 → NP_649017.1  uncharacterized protein Dmel_CG7430, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649017.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVL7
    Related
    FBpp0074906
    Conserved Domains (4) summary
    PRK06327
    Location:35 → 504
    PRK06327; dihydrolipoamide dehydrogenase; Validated
    pfam00070
    Location:211 → 290
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam02852
    Location:385 → 491
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
    cl21454
    Location:35 → 74
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. NM_001275071.1 → NP_001262000.1  uncharacterized protein Dmel_CG7430, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262000.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVL7
    Conserved Domains (4) summary
    PRK06327
    Location:35 → 504
    PRK06327; dihydrolipoamide dehydrogenase; Validated
    pfam00070
    Location:211 → 290
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam02852
    Location:385 → 491
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
    cl21454
    Location:35 → 74
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VVL7 Q9VVL7

Gene LinkOut

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