ar.L androgen receptor L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ar.L
Official Full Name: androgen receptor L homeolog
Primary source: Xenbase:XB-GENE-479433
Locus tag: XELAEV_18002878mg
See related: EnsemblRapid:ENSXLAG00005031532 AllianceGenome:Xenbase:XB-GENE-479433
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ar; ADR; Xl alpha AR
Summary: Predicted to enable several functions, including estrogen response element binding activity; nuclear receptor activity; and zinc ion binding activity. Predicted to act upstream of or within androgen receptor signaling pathway; male gonad development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in musculoskeletal system; nervous system; respiratory system; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; attention deficit hyperactivity disorder; disorder of sexual development (multiple); reproductive organ cancer (multiple); and spinal muscular atrophy (multiple). Orthologous to human AR (androgen receptor). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (30541025..30689464, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694828.1 (812014..958903)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables estrogen response element binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables steroid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within androgen receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within male gonad development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nuclear receptor-mediated steroid hormone signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

Names: androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) L homeolog

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_001090884.1: Suppressed sequence

Description

NM_001090884.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.