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nup62.L nucleoporin 62kDa L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399447, updated on 17-Aug-2024

Summary

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Official Symbol
nup62.L
Official Full Name
nucleoporin 62kDa L homeolog
Primary source
Xenbase:XB-GENE-6253895
Locus tag
XELAEV_18038559mg
See related
EnsemblRapid:ENSXLAG00005024637
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
p62; ibsn; sndi; il4i1; nup62
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Genomic context

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Location:
chromosome: 8L
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (25247288..25288795)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (16493466..16535164, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) L homeolog Neighboring gene cyclic nucleotide gated channel alpha 2 L homeolog Neighboring gene dynein axonemal assembly factor 6 L homeolog Neighboring gene gamma-aminobutyric acid receptor subunit beta-4 Neighboring gene gama-aminobutyric acid (GABA) A receptor, alpha 3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex. Schwarz-Herion K, et al. J Mol Biol, 2007 Jul 20. PMID 17544442
  2. Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex. Chug H, et al. Science, 2015 Oct 2. PMID 26292704
  3. Nuclear pore complex glycoprotein p62 of Xenopus laevis and mouse: cDNA cloning and identification of its glycosylated region. Cordes V, et al. Eur J Cell Biol, 1991 Jun. PMID 1915419
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. found the phenylalanine-glycine (FG)-repeat domain of p62, but not of p58 and p54, to be of mobile and flexible nature
    Title: Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC131375

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of nuclear pore IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
  
part_of nuclear pore IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nucleoporin 62kDa L homeolog
Names
nuclear pore complex glycoprotein p62

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090870.1 → NP_001084339.1  nucleoporin 62kDa L homeolog

    See identical proteins and their annotated locations for NP_001084339.1

    Status: PROVISIONAL

    Source sequence(s)
    BC106600
    UniProtKB/TrEMBL
    A0A974H7K6, Q91349
    Related
    ENSXLAP00005073059.1, ENSXLAT00005074623.1
    Conserved Domains (3) summary
    pfam05064
    Location:349 → 454
    Nsp1_C; Nsp1-like C-terminal region
    pfam15967
    Location:124 → 523
    Nucleoporin_FG2; Nucleoporin FG repeated region
    pfam16043
    Location:389 → 526
    DUF4795; Domain of unknown function (DUF4795)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    25247288..25288795
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018228791.2 → XP_018084280.1  nucleoporin 62kDa L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0TH90

  2. XM_041571982.1 → XP_041427916.1  nucleoporin 62kDa L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LET0
    Related
    ENSXLAP00005073148.1, ENSXLAT00005074712.1
    Conserved Domains (1) summary
    TIGR02168
    Location:342 → 549
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_041571983.1 → XP_041427917.1  nucleoporin 62kDa L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LEG1
    Conserved Domains (1) summary
    TIGR02168
    Location:341 → 548
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  4. XM_041571984.1 → XP_041427918.1  nucleoporin 62kDa L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1LEF4
    Related
    ENSXLAP00005073095.1, ENSXLAT00005074657.1
    Conserved Domains (1) summary
    TIGR02168
    Location:295 → 502
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  5. XM_041571985.1 → XP_041427919.1  nucleoporin 62kDa L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1LFW8
    Conserved Domains (1) summary
    TIGR02168
    Location:294 → 501
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
Heading Accession and Version

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