tdg.S thymine DNA glycosylase S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: tdg.S
Official Full Name: thymine DNA glycosylase S homeolog
Primary source: Xenbase:XB-GENE-1006134
Locus tag: XELAEV_18021295mg
See related: EnsemblRapid:ENSXLAG00005014730
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: tdg
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Genomic context

Location:: chromosome: 3S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3S	NC_054376.1 (97489710..97508523, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3S	NC_030729.1 (95617983..95636167, complement)

Chromosome 3S - NC_054376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRL4(Cdt2) targets thymine DNA glycosylase (TDG), a base excision repair enzyme that is involved in DNA demethylation
Title: Thymine DNA glycosylase is a CRL4Cdt2 substrate.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA N-glycosylase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables mismatch base pair DNA N-glycosylase activity	IEA Inferred from Electronic Annotation more info
enables pyrimidine-specific mismatch base pair DNA N-glycosylase activity	IEA Inferred from Electronic Annotation more info
enables uracil DNA N-glycosylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within base-excision repair, AP site formation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: thymine DNA glycosylase S homeolog

Names: thymine-DNA glycosylase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090821.1 → NP_001084290.1 thymine DNA glycosylase S homeolog

See identical proteins and their annotated locations for NP_001084290.1

Status: PROVISIONAL

Source sequence(s)

BC077465

UniProtKB/TrEMBL

A0A974DBG3, Q6AZQ5

Conserved Domains (1) summary

cl00483
Location:2 → 363

UDG_like; Uracil-DNA glycosylases (UDG) and related enzymes

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

97489710..97508523 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)