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tob2.L transducer of ERBB2, 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399353, updated on 4-Nov-2024

Summary

Official Symbol
tob2.L
Official Full Name
transducer of ERBB2, 2 L homeolog
Primary source
Xenbase:XB-GENE-6254034
Locus tag
XELAEV_18023643mg
See related
EnsemblRapid:ENSXLAG00005025163 AllianceGenome:Xenbase:XB-GENE-6254034
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tob2; tob4; tobl; trob2
Summary
Predicted to enable transcription corepressor activity. Predicted to act upstream of or within regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Is expressed in genital system; mesoderm; musculoskeletal system; and visual system. Orthologous to human TOB2 (transducer of ERBB2, 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See tob2.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (118155878..118169183)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (112830817..112842375)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene aconitase 2 L homeolog Neighboring gene PHD finger protein 5A L homeolog Neighboring gene GTP binding protein 1 L homeolog Neighboring gene Josephin domain containing 1 L homeolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transducer of ERBB2, 2 L homeolog
Names
Tob

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090713.1NP_001084182.1  transducer of ERBB2, 2 L homeolog

    See identical proteins and their annotated locations for NP_001084182.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073529
    UniProtKB/TrEMBL
    A0A974HPI3, Q90YB9
    Related
    ENSXLAP00005074749.1, ENSXLAT00005076329.1
    Conserved Domains (1) summary
    pfam07742
    Location:1111
    BTG; BTG family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    118155878..118169183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589220.1XP_041445154.1  transducer of ERBB2, 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974HPI3, Q90YB9
    Related
    ENSXLAP00005074709.1, ENSXLAT00005076290.1
    Conserved Domains (1) summary
    pfam07742
    Location:1111
    BTG; BTG family