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ralb.L v-ral simian leukemia viral oncogene homolog B L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399338, updated on 4-Nov-2024

Summary

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Official Symbol
ralb.L
Official Full Name
v-ral simian leukemia viral oncogene homolog B L homeolog
Primary source
Xenbase:XB-GENE-6254042
Locus tag
XELAEV_18044367mg
See related
EnsemblRapid:ENSXLAG00005018507 AllianceGenome:Xenbase:XB-GENE-6254042
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ralb; Ral B; xralb; ralb-a; ralb-b
Summary
Predicted to enable G protein activity; GDP binding activity; and GTP binding activity. Acts upstream of or within several processes, including Ras protein signal transduction; fibroblast growth factor receptor signaling pathway; and regulation of developmental pigmentation. Predicted to be located in midbody and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ralb.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (56869587..56882474)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (46315062..46328006)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene transcription factor CP2-like 1 L homeolog Neighboring gene GLI family zinc finger 2 L homeolog Neighboring gene inhibin subunit beta B L homeolog Neighboring gene SEC22 homolog A, vesicle trafficking protein L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the Ras signalling pathway. Lebreton S, et al. J Cell Sci, 2003 Nov 15. PMID 14576358
  2. Characterization of Xenopus RalB and its involvement in F-actin control during early development. Moreau J, et al. Dev Biol, 1999 May 15. PMID 10328920
  3. RLIP mediates downstream signalling from RalB to the actin cytoskeleton during Xenopus early development. Lebreton S, et al. Mech Dev, 2004 Dec. PMID 15511640
  4. Identification and characterization in Xenopus of XsmgGDS, a RalB binding protein. Iouzalen N, et al. Biochem Biophys Res Commun, 1998 Sep 18. PMID 9753634
  5. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC132175

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
  
enables GDP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within Ras protein signal transduction IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within fibroblast growth factor receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of developmental pigmentation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in midbody IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ras-related protein ralB-A
Names
XRalB-A
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
NP_001084154.1
XP_041431492.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090685.1 → NP_001084154.1  ras-related protein ralB-A

    See identical proteins and their annotated locations for NP_001084154.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108805
    UniProtKB/Swiss-Prot
    Q32N67, Q9YH09
    UniProtKB/TrEMBL
    A0A1L8EVG4, A0A974BYD0
    Related
    ENSXLAP00005054705.1, ENSXLAT00005055883.1
    Conserved Domains (1) summary
    cd04139
    Location:15 → 178
    RalA_RalB; Ral (Ras-like) family containing highly homologous RalA and RalB

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    56869587..56882474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575558.1 → XP_041431492.1  ras-related protein ralB-A isoform X1

    UniProtKB/Swiss-Prot
    Q32N67, Q9YH09
    UniProtKB/TrEMBL
    A0A1L8EVG4, A0A974BYD0
    Conserved Domains (1) summary
    cd04139
    Location:15 → 178
    RalA_RalB; Ral (Ras-like) family containing highly homologous RalA and RalB
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9YH09.1 GenPept UniProtKB/Swiss-Prot:Q9YH09

Gene LinkOut

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Molecular Biology Databases
Research Materials