U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cers5.L ceramide synthase 5 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399185, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
cers5.L
Official Full Name
ceramide synthase 5 L homeolog
Primary source
Xenbase:XB-GENE-17344555
Locus tag
XELAEV_18013644mg
See related
EnsemblRapid:ENSXLAG00005027303 AllianceGenome:Xenbase:XB-GENE-17344555
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
trh4; lass5; wu:fb79b03
Summary
Predicted to enable DNA binding activity and sphingosine N-acyltransferase activity. Predicted to act upstream of or within ceramide biosynthetic process. Predicted to be located in membrane and nucleus. Orthologous to human CERS5 (ceramide synthase 5). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cers5.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (157278846..157328008, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (151374095..151422564, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene glycerol-3-phosphate dehydrogenase 1 L homeolog Neighboring gene cytochrome c oxidase assembly factor COX14 L homeolog Neighboring gene LIM domain and actin binding 1 L homeolog Neighboring gene fibronectin type III domain containing 3A L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sphingolipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ceramide synthase 5 L homeolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090439.1 → NP_001083908.1  ceramide synthase 5 L homeolog

    See identical proteins and their annotated locations for NP_001083908.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072190
    UniProtKB/TrEMBL
    A0A974DSA3, A0A974HWI6, Q8QGA3
    Related
    ENSXLAP00005081297.1, ENSXLAT00005082908.1
    Conserved Domains (2) summary
    smart00724
    Location:131 → 331
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:81 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    157278846..157328008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580923.1 → XP_041436857.1  ceramide synthase 5 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1M592, A0A974HWI6
    Related
    ENSXLAP00005081594.1, ENSXLAT00005083205.1
    Conserved Domains (2) summary
    smart00724
    Location:131 → 331
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:81 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.