ufd1.S ubiquitin recognition factor in ER associated degradation 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ufd1.S
Official Full Name: ubiquitin recognition factor in ER associated degradation 1 S homeolog
Primary source: Xenbase:XB-GENE-963692
Locus tag: XELAEV_18010539mg
See related: EnsemblRapid:ENSXLAG00005010703 AllianceGenome:Xenbase:XB-GENE-963692
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ufd1; ufd1l; ufd1l.S
Summary: Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to act upstream of or within proteasomal protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Human ortholog(s) of this gene implicated in DiGeorge syndrome and schizophrenia. Orthologous to human UFD1 (ubiquitin recognition factor in ER associated degradation 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (143011068..143029585, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (127255962..127274512, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables polyubiquitin modification-dependent protein binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within proteasomal protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of VCP-NPL4-UFD1 AAA ATPase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ubiquitin fusion degradation protein 1 homolog

Names: ubiquitin fusion degradation 1 like S homeolog; ubiquitin fusion degradation 1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090169.1 → NP_001083638.1 ubiquitin fusion degradation protein 1 homolog

See identical proteins and their annotated locations for NP_001083638.1

Status: PROVISIONAL

Source sequence(s)

BC061930

UniProtKB/TrEMBL

A0A974DUQ5, Q6P704, Q9DG03

Related

ENSXLAP00005031602.1, ENSXLAT00005032373.1

Conserved Domains (1) summary

pfam03152
Location:19 → 193

UFD1; Ubiquitin fusion degradation protein UFD1

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

143011068..143029585 complement

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GenBank, FASTA, Sequence Viewer (Graphics)