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lrrn1.S leucine rich repeat neuronal 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399019, updated on 4-Nov-2024

Summary

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Official Symbol
lrrn1.S
Official Full Name
leucine rich repeat neuronal 1 S homeolog
Primary source
Xenbase:XB-GENE-18006546
Locus tag
XELAEV_18025838mg
See related
EnsemblRapid:ENSXLAG00005018754 AllianceGenome:Xenbase:XB-GENE-18006546
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
nlrr-1; nlrr-6; figler3; lrrn1-a; lrrn1-b; xnlrr-1; XlNLRR-6
Summary
Predicted to be located in extracellular matrix; extracellular space; and synaptic membrane. Orthologous to human LRRN1 (leucine rich repeat neuronal 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lrrn1.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (108920269..108932979)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (102454469..102467283)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene tRNA nucleotidyl transferase, CCA-adding, 1 S homeolog Neighboring gene cereblon S homeolog Neighboring gene histone-lysine N-methyltransferase SETMAR-like Neighboring gene inositol 1,4,5-trisphosphate receptor type 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68797

Gene Ontology Provided by Xenbase

Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC399019

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090141.1 → NP_001083610.1  uncharacterized protein LOC399019 precursor

    See identical proteins and their annotated locations for NP_001083610.1

    Status: PREDICTED

    Source sequence(s)
    BC061939
    UniProtKB/TrEMBL
    O73675, Q6P6Z7
    Related
    ENSXLAP00005055351.1, ENSXLAT00005056556.1
    Conserved Domains (9) summary
    smart00408
    Location:441 → 508
    IGc2; Immunoglobulin C-2 Type
    smart00082
    Location:372 → 418
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:50 → 298
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:431 → 518
    I-set; Immunoglobulin I-set domain
    sd00031
    Location:75 → 97
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:98 → 121
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00041
    Location:538 → 602
    fn3; Fibronectin type III domain
    pfam12799
    Location:97 → 137
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:97 → 156
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    108920269..108932979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041591256.1 → XP_041447190.1  uncharacterized protein LOC399019 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GHI9, A0A974D2Q6, O73675
    Conserved Domains (8) summary
    smart00013
    Location:32 → 76
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:372 → 418
    LRRCT; Leucine rich repeat C-terminal domain
    COG4886
    Location:66 → 350
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:75 → 97
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:98 → 121
    LRR_RI; leucine-rich repeat [structural motif]
    pfam07679
    Location:431 → 518
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:435 → 440
    Ig; Ig strand A' [structural motif]
    cl21522
    Location:538 → 602
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_018259508.2 → XP_018114997.1  uncharacterized protein LOC399019 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GHI9, A0A974D2Q6, O73675
    Related
    ENSXLAP00005055356.1, ENSXLAT00005056561.1
    Conserved Domains (8) summary
    smart00013
    Location:32 → 76
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:372 → 418
    LRRCT; Leucine rich repeat C-terminal domain
    COG4886
    Location:66 → 350
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:75 → 97
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:98 → 121
    LRR_RI; leucine-rich repeat [structural motif]
    pfam07679
    Location:431 → 518
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:435 → 440
    Ig; Ig strand A' [structural motif]
    cl21522
    Location:538 → 602
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein Strain
Heading Accession and Version

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