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haao.L 3-hydroxyanthranilate 3,4-dioxygenase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398998, updated on 4-Nov-2024

Summary

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Official Symbol
haao.L
Official Full Name
3-hydroxyanthranilate 3,4-dioxygenase L homeolog
Primary source
Xenbase:XB-GENE-6254902
Locus tag
XELAEV_18026161mg
See related
EnsemblRapid:ENSXLAG00005009192 AllianceGenome:Xenbase:XB-GENE-6254902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
haao
Summary
Predicted to enable 3-hydroxyanthranilate 3,4-dioxygenase activity and ferrous iron binding activity. Predicted to act upstream of or within NAD biosynthetic process and quinolinate biosynthetic process. Predicted to be located in cytosol. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See haao.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (9211612..9271556)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (8495494..8551175)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108716428 Neighboring gene ZFP36 ring finger protein-like 2 L homeolog Neighboring gene transfer RNA isoleucine (anticodon UAU) Neighboring gene cytochrome c oxidase subunit 7A-related protein, mitochondrial Neighboring gene potassium channel, voltage gated modifier subfamily G, member 3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68644

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 3-hydroxyanthranilate 3,4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables 3-hydroxyanthranilate 3,4-dioxygenase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within 'de novo' NAD biosynthetic process from tryptophan IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within NAD biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within NAD biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within anthranilate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pyridine nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within quinolinate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within quinolinate biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within quinolinate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tryptophan catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
3-hydroxyanthranilate 3,4-dioxygenase
NP_001083573.1
XP_018117262.1
XP_041418057.1
XP_041418058.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090104.1 → NP_001083573.1  3-hydroxyanthranilate 3,4-dioxygenase

    See identical proteins and their annotated locations for NP_001083573.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061663
    UniProtKB/Swiss-Prot
    Q6P7I0
    Related
    ENSXLAP00005026783.1, ENSXLAT00005027515.1
    Conserved Domains (1) summary
    cl21464
    Location:4 → 149
    cupin_like; Conserved domain found in cupin and related proteins

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    9211612..9271556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562123.1 → XP_041418057.1  3-hydroxyanthranilate 3,4-dioxygenase isoform X1

    UniProtKB/TrEMBL
    A0A8J1KL51
    Related
    ENSXLAP00005026775.1, ENSXLAT00005027507.1
    Conserved Domains (2) summary
    cd06123
    Location:16 → 166
    cupin_HAO; 3-Hydroxyanthranilate-3,4-dioxygenase, cupin domain
    cl40423
    Location:190 → 280
    cupin_RmlC-like; RmlC-like cupin superfamily

  2. XM_018261773.2 → XP_018117262.1  3-hydroxyanthranilate 3,4-dioxygenase isoform X2

    UniProtKB/TrEMBL
    A0A1L8G5X2, A0A974CTE3
    Conserved Domains (2) summary
    cd06123
    Location:9 → 159
    cupin_HAO; 3-Hydroxyanthranilate-3,4-dioxygenase, cupin domain
    cl40423
    Location:183 → 273
    cupin_RmlC-like; RmlC-like cupin superfamily

  3. XM_041562124.1 → XP_041418058.1  3-hydroxyanthranilate 3,4-dioxygenase isoform X2

    UniProtKB/TrEMBL
    A0A1L8G5X2, A0A974CTE3
    Related
    ENSXLAP00005026752.1, ENSXLAT00005027485.1
    Conserved Domains (2) summary
    cd06123
    Location:9 → 159
    cupin_HAO; 3-Hydroxyanthranilate-3,4-dioxygenase, cupin domain
    cl40423
    Location:183 → 273
    cupin_RmlC-like; RmlC-like cupin superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P7I0.1 GenPept UniProtKB/Swiss-Prot:Q6P7I0

Gene LinkOut

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