ppp1r8.L protein phosphatase 1 regulatory subunit 8 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ppp1r8.L
Official Full Name: protein phosphatase 1 regulatory subunit 8 L homeolog
Primary source: Xenbase:XB-GENE-865286
Locus tag: XELAEV_18012048mg
See related: EnsemblRapid:ENSXLAG00005031180 AllianceGenome:Xenbase:XB-GENE-865286
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ard1; ard-1; nipp1; nipp-1; ppp1r8
Summary: Predicted to enable mRNA binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be located in nuclear speck. Orthologous to human PPP1R8 (protein phosphatase 1 regulatory subunit 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2L

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (59086921..59109941)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (56616170..56639156)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine phosphatase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nuclear speck	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein phosphatase 1 regulatory subunit 8 L homeolog

Names: protein phosphatase 1, regulatory (inhibitor) subunit 8; protein phosphatase 1, regulatory subunit 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090059.1 → NP_001083528.1 protein phosphatase 1 regulatory subunit 8 L homeolog

See identical proteins and their annotated locations for NP_001083528.1

Status: PROVISIONAL

Source sequence(s)

BC060757

UniProtKB/TrEMBL

A0A974DPM2, Q6P9H8

Related

ENSXLAP00005093375.1, ENSXLAT00005095058.1

Conserved Domains (3) summary

COG1716
Location:39 → 120

FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]

cd00060
Location:25 → 117

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

pfam11945
Location:96 → 268

WASH_WAHD; WAHD domain of WASH complex