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epb41l3.L erythrocyte membrane protein band 4.1-like 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398970, updated on 4-Nov-2024

Summary

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Official Symbol
epb41l3.L
Official Full Name
erythrocyte membrane protein band 4.1-like 3 L homeolog
Primary source
Xenbase:XB-GENE-1006081
Locus tag
XELAEV_18031863mg
See related
EnsemblRapid:ENSXLAG00005035214 AllianceGenome:Xenbase:XB-GENE-1006081
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dal1; dal-1; epb41l3
Summary
Predicted to enable actin binding activity and structural molecule activity. Predicted to act upstream of or within cortical actin cytoskeleton organization. Predicted to be located in cell-cell junction. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See epb41l3.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
29
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (112903913..113092952)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (105932500..106044231)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 200C L homeolog Neighboring gene uncharacterized LOC108719205 Neighboring gene uncharacterized LOC121394713 Neighboring gene uncharacterized LOC121394714 Neighboring gene zinc finger and BTB domain containing 14 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68473

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell-cell junction ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
erythrocyte membrane protein band 4.1-like 3 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090051.1 → NP_001083520.1  erythrocyte membrane protein band 4.1-like 3 L homeolog

    See identical proteins and their annotated locations for NP_001083520.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060449
    UniProtKB/TrEMBL
    A0A974CNE0, Q6PA55
    Conserved Domains (7) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam00373
    Location:192 → 299
    FERM_M; FERM central domain
    pfam04382
    Location:519 → 563
    SAB; SAB domain
    pfam05902
    Location:659 → 737
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:396 → 436
    FA; FERM adjacent (FA)
    pfam09379
    Location:112 → 172
    FERM_N; FERM N-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    112903913..113092952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041565330.1 → XP_041421264.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X7

    UniProtKB/TrEMBL
    A0A8J1KYB9
    Conserved Domains (2) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  2. XM_018266358.2 → XP_018121847.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0VEH1
    Conserved Domains (5) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:758 → 805
    SAB; SAB domain
    pfam05902
    Location:1295 → 1400
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:396 → 439
    FA; FERM adjacent (FA)

  3. XM_018266361.2 → XP_018121850.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A1L8FYK9, A0A974CPK9

  4. XM_018266362.2 → XP_018121851.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X6

    UniProtKB/TrEMBL
    A0A8J0VMM3, A0A974CP30

  5. XM_018266369.2 → XP_018121858.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X16

    UniProtKB/TrEMBL
    A0A8J0VHC8, A0A974CP30

  6. XM_041565334.1 → XP_041421268.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X21

    UniProtKB/TrEMBL
    A0A8J1KWX0, A0A974CP30
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  7. XM_041565336.1 → XP_041421270.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X23

    UniProtKB/TrEMBL
    A0A8J1KVD1, A0A974CP30
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  8. XM_018266360.2 → XP_018121849.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0VH78

  9. XM_018266363.2 → XP_018121852.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X8

    UniProtKB/TrEMBL
    A0A8J0VHC4, A0A974HE51

  10. XM_018266365.2 → XP_018121854.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X10

    UniProtKB/TrEMBL
    A0A8J0VEH7, A0A974HE51

  11. XM_018266367.2 → XP_018121856.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X12

    UniProtKB/TrEMBL
    A0A8J0VIF3, A0A974HE51
    Related
    ENSXLAP00005105406.1, ENSXLAT00005107455.1

  12. XM_041565328.1 → XP_041421262.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1KVC0
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  13. XM_041565329.1 → XP_041421263.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1KWW4
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  14. XM_041565331.1 → XP_041421265.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X9

    UniProtKB/TrEMBL
    A0A8J1KVC5, A0A974HE51
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  15. XM_041565332.1 → XP_041421266.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X13

    UniProtKB/TrEMBL
    A0A8J1KVD2, A0A974HE51
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  16. XM_018266373.2 → XP_018121862.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X18

    UniProtKB/TrEMBL
    A0A8J0VIF6, A0A974CP30

  17. XM_041565333.1 → XP_041421267.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X17

    UniProtKB/TrEMBL
    A0A8J1KVC7, A0A974CP30
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  18. XM_018266374.2 → XP_018121863.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X19

    UniProtKB/TrEMBL
    A0A8J0VMM8, A0A974CP30
    Related
    ENSXLAP00005105500.1, ENSXLAT00005107552.1

  19. XM_041565335.1 → XP_041421269.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X22

    UniProtKB/TrEMBL
    A0A8J1KYC4, A0A974CP30
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  20. XM_018266375.2 → XP_018121864.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X20

    UniProtKB/TrEMBL
    A0A8J0VHD3, A0A974CP30

  21. XM_018266366.2 → XP_018121855.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X11

    UniProtKB/TrEMBL
    A0A8J0VH83, A0A974HE51
    Related
    ENSXLAP00005105359.1, ENSXLAT00005107407.1

  22. XM_041565338.1 → XP_041421272.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X25

    UniProtKB/TrEMBL
    A0A8J1KVD8, A0A974CQQ5
    Related
    ENSXLAP00005105642.1, ENSXLAT00005107702.1
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  23. XM_018266368.2 → XP_018121857.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X14

    UniProtKB/TrEMBL
    A0A8J0VMM5, A0A974HE51
    Related
    ENSXLAP00005105436.1, ENSXLAT00005107485.1

  24. XM_018266370.2 → XP_018121859.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X15

    UniProtKB/TrEMBL
    A0A8J0VEI6, A0A974HE51

  25. XM_041565337.1 → XP_041421271.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X24

    UniProtKB/TrEMBL
    A0A8J1KVD7, A0A974CQQ5
    Related
    ENSXLAP00005105534.1, ENSXLAT00005107590.1
    Conserved Domains (2) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family

  26. XM_041565327.1 → XP_041421261.1  erythrocyte membrane protein band 4.1-like 3 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0VEH1
    Conserved Domains (5) summary
    smart00295
    Location:110 → 299
    B41; Band 4.1 homologues
    cd13184
    Location:294 → 387
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:758 → 805
    SAB; SAB domain
    pfam05902
    Location:1295 → 1400
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:396 → 439
    FA; FERM adjacent (FA)
Nucleotide Protein Strain
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