uck1.S uridine-cytidine kinase 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: uck1.S
Official Full Name: uridine-cytidine kinase 1 S homeolog
Primary source: Xenbase:XB-GENE-961188
Locus tag: XELAEV_18041618mg
See related: EnsemblRapid:ENSXLAG00005018424 AllianceGenome:Xenbase:XB-GENE-961188
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: uck1; uck1-A
Summary: Predicted to enable cytidine kinase activity and uridine kinase activity. Predicted to act upstream of or within CTP salvage and UMP salvage. Predicted to be located in cytoplasm. Orthologous to human UCK1 (uridine-cytidine kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8S

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (32385011..32390850)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (32254839..32260682)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables cytidine kinase activity	IEA Inferred from Electronic Annotation more info
enables cytidine kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables ribosylnicotinamide kinase activity	IEA Inferred from Electronic Annotation more info
enables uridine kinase activity	IEA Inferred from Electronic Annotation more info
enables uridine kinase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within CTP salvage	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within CTP salvage	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within UMP salvage	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within UMP salvage	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uridine-cytidine kinase 1-A

Names: Cytidine monophosphokinase 1-A; UCK 1-A; Uridine monophosphokinase 1-A

NP_001083512.1

EC 2.7.1.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090043.1 → NP_001083512.1 uridine-cytidine kinase 1-A

See identical proteins and their annotated locations for NP_001083512.1

Status: PROVISIONAL

Source sequence(s)

BC060421

UniProtKB/Swiss-Prot

Q6PA79

UniProtKB/TrEMBL

A0A974C2K6

Related

ENSXLAP00005054470.1, ENSXLAT00005055644.1

Conserved Domains (2) summary

COG0572
Location:16 → 226

Udk; Uridine kinase [Nucleotide transport and metabolism]

cd02023
Location:19 → 224

UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...